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Scientists engineer safe, virus-resistant E coli for research

Drug Discovery World

In a step forward for genetic engineering and synthetic biology, US researchers have modified E coli bacteria to be immune to infection by all natural viruses tested so far. The team used two safeguard methods to prevent the bacteria and their modified genes from escaping into the wild.

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Cataloging nature’s hidden arsenal: Viruses that infect bacteria

Scienmag

A new genetic approach can accelerate the study of phage-microbe interactions with implications for health, agriculture, and climate Credit: Wikimedia Commons Scientists are continually searching for new and improved ways to deal with bacteria, be it to eliminate disease-causing strains or to modify potentially beneficial strains.

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Flipping light on-off turns bacteria into chemical factories

Scienmag

Credit: Avalos Lab/Princeton University Researchers at Princeton University have created a new and improved way to more precisely control genetically engineered bacteria: by simply switching the lights on and off. Working in E.

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Good Gut Bacteria Can Aid in Healing Intestines Damaged by IBD

XTalks

A study published in Nature on July 30, 2020 states that good bacteria living in our gut can do much more than just help digest food and boost our immune system. According to studies conducted by researchers at Cincinnati Children’s Hospital, the bacteria can help heal damaged intestinal tissues.

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Global advances in synthetic biology

Drug Discovery World

The rapidly growing area of synthetic biology – including molecular biology, biotechnology, biophysics, and genetic engineering – is having a marked impact on the drug discovery landscape. It appears to neutralise even drug-resistant bacteria. . diff, and several other deadly pathogens.

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Could Fluoride be the Solution to Antibiotic Resistance? A New Study Weighs In

The Pharma Data

But scientists at the University of California (UC), Santa Barbara, believe fluoride may offer hope in the fight against antibiotic-resistant bacteria. ” This method may also provide significant cost-savings, particularly in relation to antibiotic-driven selection in research laboratories. ” Source link.

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The evolution of assays for immuno-oncology research

Drug Discovery World

The first such research dates back to 1891, when William Coley attempted to inject heat-inactivated bacteria to treat osteosarcoma. Genetically engineered mouse models (GEMM) recapitulate the stromal biology of different human cancers including the tumour microenvironment that regulates the disease process. doi:10.15252/emmm.201606857pmid:[link]