Scienmag

SEPTEMBER 8, 2020

Credit: Avalos Lab/Princeton University Researchers at Princeton University have created a new and improved way to more precisely control genetically engineered bacteria: by simply switching the lights on and off. Working in E.

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XTalks

JULY 31, 2020

A study published in Nature on July 30, 2020 states that good bacteria living in our gut can do much more than just help digest food and boost our immune system. According to studies conducted by researchers at Cincinnati Children’s Hospital, the bacteria can help heal damaged intestinal tissues.

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Drug Discovery World

MARCH 21, 2023

In a step forward for genetic engineering and synthetic biology, US researchers have modified E coli bacteria to be immune to infection by all natural viruses tested so far. The team used two safeguard methods to prevent the bacteria and their modified genes from escaping into the wild.

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pharmaphorum

MAY 7, 2021

CRISPR’s deal with Nkarta aims to create genetically engineered NK cells, which are harvested and used to create a bank of “off the shelf” cells that can administered to patients like a drug. The post CRISPR Therapeutics begins natural killer cell cancer tie-up with Nkarta appeared first on.

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Drug Discovery World

NOVEMBER 17, 2022

The rapidly growing area of synthetic biology – including molecular biology, biotechnology, biophysics, and genetic engineering – is having a marked impact on the drug discovery landscape. It appears to neutralise even drug-resistant bacteria. . diff, and several other deadly pathogens.

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The Pharma Data

JANUARY 4, 2021

But scientists at the University of California (UC), Santa Barbara, believe fluoride may offer hope in the fight against antibiotic-resistant bacteria. “Essentially, what Justin did was to create a series of DNA instructions you can give to cells that will enable them to survive when fluoride is around,” said O’Malley.

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The Pharma Data

OCTOBER 26, 2020

These mAbs are already of human origin and functionally optimized for high potency by the donor’s immune system; hence, they technically do not require genetic engineering or further optimization to achieve full functionality.

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The Pharma Data

JANUARY 19, 2021

A naturally occurring system for tuning CRISPR-Cas9 expressing in bacteria, identified in a study published in Cell , could have implications for gene editing therapies as well. In bacteria with unaltered tracr-L, levels of CRISPR-related genes were low. The authors found that tracr-L redirects Cas9 in S.

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Roots Analysis

AUGUST 31, 2023

coli bacteria, as well as lambda bacteriophage, can adapt to the alterations in the composition of their nutrient medium. Therefore, although a gene switch may induce programmed cell death in culture cells to mitigate adverse events caused by engineered cell therapies, it could be considered insufficient / dangerous for clinical practice.

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Drug Discovery World

FEBRUARY 15, 2023

The first such research dates back to 1891, when William Coley attempted to inject heat-inactivated bacteria to treat osteosarcoma. Genetically engineered mouse models (GEMM) recapitulate the stromal biology of different human cancers including the tumour microenvironment that regulates the disease process. doi:10.15252/emmm.201606857pmid:[link]

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