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Evaluating methods targeting Protein-Protein Interactions

pharmaphorum

Whereas targets like receptors contain an obvious ligand-binding site for drug molecules to interact with, PPIs comprise a more complex structure. The interface is highly hydrophobic, hence any compounds containing water would be repelled. What does this mean for clinical research? Charlotte Di Salvo.

Protein 126
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Addressing the challenge of salt forms in drug discovery

Drug Discovery World

Some 5% of commercially available research compounds aresold as salt forms. By selecting the correct salt form for an assay or as a reagent, scientists can optimise their research projects, says Andrievs Auseklis Auzin, Developer, Molport, Latvia. The research chemical supply market. Suppose you want to makeup a 0.1

Drugs 52
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Can artificial intelligence help craft new medicines?

Drug Discovery World

Here, new bioassay technologies helped testing, but more definite answers were required. Expression patterns, proteomic profiles, bioassay results, and structures could now be captured en masse in normal and disease conditions. The MorCVD database contains all the human proteins that can be potentially involved in heart disease.

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Reflecting on PEGS Europe 2023 

Drug Discovery World

Panel moderators included Ulf Grawunder from T-CURX and Astero Klampatsa from the Insitute of Cancer Research, and panellists included John Anderson from University College London, Michael Hudecek from University of Applied Sciences Wuerzburg-Schweinfurt, as well as Sebastian Kobold from Klinikum de Universität München.

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Let's Quit Sugar With Audiobook – Let's Quit Sugar

The Pharma Data

Fructose Containing Sugars at Normal Levels of Consumption Do Not Effect Adversely Components of the Metabolic Syndrome and Risk Factors for Cardiovascular Disease. Experimental Diabetes Research. Effects of almond consumption on the reduction of LDL-cholesterol: a discussion of potential mechanisms and future research directions.

Insulin 52