Remove Bioassay Remove Engineer Remove Genotoxicity Remove Research
article thumbnail

Accelerating NDA filing through faster carcinogenicity assessment

Drug Discovery World

While the discovery phase – which includes target discovery, target validation, lead compound identification, and lead compound optimisation – averages several years and $200 million, the majority of the research, time, and financial spend takes place downstream in drug development. In practice, this was typically conducted in rats and mice.

article thumbnail

Let's Quit Sugar With Audiobook – Let's Quit Sugar

The Pharma Data

Experimental Diabetes Research. Effects of almond consumption on the reduction of LDL-cholesterol: a discussion of potential mechanisms and future research directions. Exposure to sorbitol during lactation causes metabolic alterations and genotoxic effects in rat offspring. DOI: 10.1016/j.reprotox.2014.09.007. 2014.09.007.

Insulin 52