Pharmaceutical Technology
AUGUST 22, 2022
They also offer enhanced bioavailability, exact dosing and an extended shelf life. Fixed-dose combination (FDC) systems aim to increase patient compliance in therapies involving two or more active drugs. Softgel capsules, containing a liquid, paste or emulsion active ingredient, are trusted and favoured by many patients.
Camargo
DECEMBER 22, 2021
Clinical pharmacology may also involve comparative bioavailability analyses, which are generally required for drug formulation bridging studies, to demonstrate bioequivalence. These are put in place to ensure product quality in compliance with FDA requirements. Biowaiver Eligibility.
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Cloudbyz
MARCH 5, 2024
Administration and Dosage: Due to their nature, biologics are often administered via injection or infusion, which can affect patient compliance and convenience. Oral Bioavailability: Developing small molecules that are effectively absorbed when administered orally, while also being stable in the digestive system, can be complex.
Camargo
SEPTEMBER 30, 2021
Drug product formulation should be as simple as possible, but carefully executed to account for the characteristics of the intended administration route and dosing regimen and to facilitate successful manufacturing, storage, shipping, and compliance in the clinic and eventually on the market. Species Selection. Case report format and design.
Pharmaceutical Technology
JUNE 14, 2023
Many small and mid-cap companies lack the expertise for regulatory compliance and high containment facilities and thus seek to outsource NMEs (New Molecular Entities) requiring special handling. A number of high-impact milling methods, including ball, hammer, pin, and disc mills, have been adopted to meet this need.
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