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Why early participant engagement is now a top priority in genetic disease research

pharmaphorum

JANUARY 18, 2023

In 2016, scientists behind a study called the Resilience Project analysed genetic data from 589,000+ people and found 13 adults who carried genetic variants that should have resulted in serious – even deadly – childhood disease, but who were apparently healthy.

Genetic Disease 83
Genetic Disease Genetics Research Genome 83
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HFpEF vs. HFrEF: How To Improve Heart Failure Drug Development

XTalks

APRIL 15, 2021

A 2015 study published in Nature Genetics found that the availability of human genetic data made investigational drugs twice as likely to pass pivotal trials and eventually be approved. Instead, the team decided to target their search to the gene, promoter and enhancer regions, based on sequences from the GeneHancer database.

Development 98
Development Drugs Genome Genomics 98
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