XTalks
SEPTEMBER 16, 2022
Having a mutation in one copy of either the EGFR and/or KRAS gene isn’t enough to lead to lung cancer. Most cancers follow the double-hit model where a mutation in the second copy of the gene is required for the cancer to form. The Double Hit. The new research shows that air pollutants can be that ‘second hit.’
Drug Discovery World
OCTOBER 30, 2023
We previously conducted a hypothesis-free study using genotype data from the UK Biobank, which resulted in the first mechanism-based stratification of endometriosis patients. SG: Chronic diseases, like endometriosis, are polygenic, caused by a complex interplay of multiple genes and other factors.
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XTalks
APRIL 15, 2021
From a total of 30 single-nucleotide polymorphisms (SNPs) in genes previously identified as being associated with blood pressure, many had a relatively neutral effect on the risk of coronary artery disease. Figure 2: Using drug-target MR to validate sympathetic nervous system genes involved in heart failure.
The Pharma Data
JULY 12, 2021
.” In the new study, Ghosh and colleagues replaced the first and last steps in preclinical drug discovery with two novel approaches developed within the UC San Diego Institute for Network Medicine (iNetMed), which unites several research disciplines to develop new solutions to advance life sciences and technology and enhance human health.
Drug Discovery World
OCTOBER 13, 2022
The DDW team spent 4-5 October, 2022 at ELRIG’s annual meeting, Drug Discovery 2022, which remains Europe’s largest meeting for life sciences industry professionals and took place at ExCel, London, UK.
The Pharma Data
APRIL 11, 2023
Another key focus at Bayer is on innovative precision oncology treatments, with an approved TRK inhibitor exclusively designed to treat tumors that have an NTRK gene fusion, the oncogenic driver of tumor growth and spread. About Bayer Bayer is a global enterprise with core competencies in the life science fields of health care and nutrition.
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