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Natural drop in insulin resistance in mid-adolescence may protect against worsening arterial stiffness if sustained

Medical Xpress

Significant physiologic decrease in insulin resistance during mid-adolescence may stop and reverse arterial stiffness progression, a paper published in the American Journal of Physiology-Endocrinology and Metabolism concludes. and the University of Eastern Finland.

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Top 15 Diabetes Drugs in 2023 by 2022 Sales Statistics

XTalks

According to AstraZeneca, the drug had strong demand across all of its approved indications and was further supported by recent guideline updates from cardiology societies. In its 2022 financial report, Sanofi reported that sales of the long-acting insulin dropped 27.6 This performance exceeded Wall Street’s expectations by 20 percent.

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Arterial stiffness may cause metabolic syndrome in adolescents via an increase in fasting insulin and LDL cholesterol

Medical Xpress

Arterial stiffness may be a novel risk factor for metabolic syndrome in teens, a new study concludes. The paper was published in the American Journal of Physiology–Heart and Circulatory Physiology. It was conducted in collaboration between the University of Bristol in the U.K., the University of Exeter in the U.K.,

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Diabetes researchers discover the potential of CIDEC protein to mitigate obesity-related cardiometabolic disease

Medical Xpress

Their study, "Endothelial-Specific Expression of CIDEC Improves High-Fat Diet-Induced Vascular and Metabolic Dysfunction," published in Diabetes focuses on vascular function and its association with metabolic diseases like insulin resistance, type 2 diabetes, and cardiovascular disease.

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Diabetes Boosts Odds for Heart Trouble 10-fold in Younger Women

The Pharma Data

Both of those factors had weaker associations with heart disease onset in women younger than 55 than lipoprotein insulin resistance (LPIR,) a newer metric for insulin resistance. Insulin resistance occurs when cells in muscles, fat and the liver don’t respond well to insulin and can’t use glucose.

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Diabetes powerfully associated with premature coronary heart disease in women

Scienmag

A new biomarker of insulin resistance was tied to a 600 percent increase in risk of premature coronary heart disease BOSTON — While deaths related to heart disease have declined among older people, studies suggest that death rates among younger patients have remained stagnant or increased slightly.

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A USD 4.2 Billion Myovant/ Pfizer Deal; Audentes Therapeutics’ ASPIRO Trial Free to Proceed; First Generic of Drug for Severe Hypoglycemia Gets Approval; Teleflex Acquires Z-Medica

Delveinsight

It is a complication associated with diabetic patients who take insulin and certain anti-diabetic tablets. The company boasts of its wide spectrum of portfolio ranging from solutions in the fields of vascular access, interventional cardiology and radiology, anesthesia, emergency medicine, surgical, urology, and respiratory care.

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