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Vertex eyes controllable genetic drugs with $1.3bn Obsidian alliance

pharmaphorum

billion in milestone payments in the deal, which will focus on using small-molecule compounds to “fine tune” the effects of genetic medicines in the body. The approach relies on the use of drug responsive domains (DRDs) on the gene-editing medicine, which can be used to either increase or decrease protein expression.

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Touchlight boosts DNA manufacturing capacity with latest expansion

Pharmaceutical Technology

As per the company, dbDNA is suitable for rapid, scalable manufacture of GMP DNA and can incorporate gene sequences of sizes ranging from 500bp to 20kb, which are typically unstable as pDNA. Biopharmaceutical companies like Pfizer and Lonza have announced licensing agreements to use the doggybone in their own respective research.

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