Drug Discovery World

JANUARY 19, 2023

This paid-for advertorial by Catalent appeared in DDW Volume 24 – Issue 1, Winter 2022/2023 One significant challenge in the manufacturing of cell and gene therapies is the production of high-quality plasmid DNA (pDNA). coli cell bank that contains the plasmid. coli residual contaminants as well as product-related impurities.

DNA 52

DNA Manufacturing Gene Therapy Gene 52

Advarra

MARCH 31, 2023

The use of engineered genetic materials in clinical trials is rapidly expanding, with potential applications for genetic vaccines, gene-modified cellular therapies, and gene therapies. IPs containing engineered genetic materials may pose risks potentially not anticipated by the clinic’s standard infection control policies.

Engineer 52

Engineer Genetics Clinical Research Research 52

Drug Discovery World

MAY 11, 2023

Gene-based therapeutics and vaccines hold immense potential for more efficient and personalised treatment and prevention of complex diseases. In these cases, injection of the viral vector vaccines induced the production of antibodies recognising platelet factor 4 (PF4) found on patients’ platelets 1.

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Production Gene Protein Vaccination 52

Drug Discovery World

FEBRUARY 8, 2023

This helps ensure a high concentration of loaded capsids and adequate removal of impurities, such as host cell proteins and DNA. In AAV therapeutics, empty capsids are those that are not packaged with the therapeutic DNA. Robustness: to be able to tolerate matrix effects (type of buffer, residual contaminants, ionic strength, etc.)

Gene Therapy 52

Gene Therapy Gene Antibody Production 52

XTalks

SEPTEMBER 14, 2020

“Vaccine Nationalism” Could Prove the Undoing of COVID-19 Containment. Tension is mounting as nations big and small jockey around industry to ensure they are first in line to access a vaccine, should one prove to be successful against COVID-19. Moderna’s COVID-19 Vaccine. The price of that prize is incalculable.

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Vaccination Vaccine Antibody Life Science 92

The Pharma Data

MAY 13, 2021

every day are contaminated with at LEAST ONE TOXIC ingredient. FACT: Food labels are NOT required to fully disclose the amounts of certain ingredients contained within foods you consume. And you’ll NEVER believe this one: Food companies do NOT even have to put a label on foods containing these DANGEROUS G.M.O.’s.

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Production Containment Genetics Doctors 52