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Cryomacs Freezing Bags – A Critical Component in the Successful Delivery of Biological Samples and Therapies

Roots Analysis

Due to the infrastructure available for processing, freezing and storing of these container systems, blood bags are the preferred container for cell therapy biopreservation. While some biobanks ( especially non-clinical ones ) use mechanical freezers for storage, liquid nitrogen is one of the most reliable cryostorage mediums.

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Delivering on the promise of gene editing

Drug Discovery World

Improve delivery: Clinical translation of gene therapy is dependent on the efficient and safe delivery of gene editing tools into cells, and this can occur either ex vivo or in vivo. In vivo approaches involve delivering the gene editing components directly into the patient. In one example, Choi et al.

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Synthetic biology tools advancing and accelerating drug discovery efforts

Drug Discovery World

The brainchild of multidisciplinary experts in computer science, physics, engineering, and biology, the field of synthetic biology has not only rapidly progressed in the last few decades but it’s also becoming more accessible and cost-effective. If there’s a mismatch between two strands, the DNA will melt away at a lower temperature.

DNA 98
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Overcoming diverging regulatory expectations to bring CGTs to market

Drug Discovery World

Over the past few decades, the incredible progress in personalised medicine has led to the development of life-saving cell and gene therapies (CGT). Within the past year, the sector saw the EU’s landmark approval of the first allogeneic T cell therapy as well as the approval of several new gene therapies in the US. billion in 2020 to $15.5

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Top five breakthroughs in advancing breast cancer therapies

Drug Discovery World

Ibrahim Ozbolat, Professor of Engineering Science and Mechanics, Biomedical Engineering and Neurosurgery, Penn State, explained how their work will impact cancer research: “We’ve developed a tool that serves as a clinical test platform to safety and accurately evaluate experimental therapies. 3D bioprinted breast cancer tumours.

In-Vivo 52
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Company Spotlight: Cue Biopharma Innovates in the Immunotherapy Space with its Immuno-STAT Platform

XTalks

With several biologics in the pipeline, including one in early stage clinical trials for head and neck cancer, the company is positioned to engineer highly specific biologics against immune targets in the body. Cell-Based Immunotherapy vs. Immune Biologics. Immunotherapy involves leveraging components of the immune system (i.e.

Protein 98
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Re-assessing the risks of drug-induced arrhythmias during drug discovery

Drug Discovery World

Although such electrophysiological systems may be more predictive of potential cardiac safety and efficacy than non-functional binding assays, many apparently attractive new drugs are still being discontinued later in development. The authors of this review introduced the concept of ‘Eroom’s Law’, which is Moore’s Law spelt backwards.

Drugs 52