Pharmaceutical Technology

FEBRUARY 3, 2023

With scientists fervently developing mRNA vaccines, nucleic acid therapeutics, and viral vector-based gene therapies, clinicians are set to have a growing number of tools available to treat a wide range of conditions, from infectious diseases to genetic disorders and more. The field of genomic medicine has reached a true turning point.

Genome 244

Genome Genomics Medicine Gene Therapy 244

Drug Discovery World

JANUARY 19, 2023

pDNA is a critical raw material for advanced therapeutics including mRNA and viral vector-based cell and gene therapies and vaccines. Plasmid DNA: a critical reagent pDNA is the starting material for the development of many cell and gene therapy products, irrespective of the mode of action. billion by 2030 (BioSpace, 11 August 2022).

DNA 52

DNA Manufacturing Gene Therapy Gene 52

Drug Discovery World

FEBRUARY 8, 2023

During AAV process development, there are numerous variables that need to be optimised to maximise the number of full capsids while minimising contaminants. Robustness: to be able to tolerate matrix effects (type of buffer, residual contaminants, ionic strength, etc.) What makes an ideal AAV analytics tool for process development?

Gene Therapy 52

Gene Therapy Gene Antibody Production 52