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Unlocking the potential of mRNA for the future treatment of rare diseases 

Drug Discovery World

As we turn our focus to new potential applications and disease areas for the platform, scientists and companies must consider the potential life-saving impact on rare, inherited diseases, says Archana Gupta , PhD, staff scientist in genetic sciences at Thermo Fisher Scientific.

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Beam makes USD 120M bet; GRAIL and Quest announce the collaboration; Brain organoids mimic infant’s brains; Improvement in T cells to kill cancer

Delveinsight

The gene-editing technologies, which have reached the clinic, CRISPR, zinc finger nucleases, and TALENs, make their edits by nicking DNA at the target site. Cambridge, Massachusetts-based Beam aims to make more precise edits with genetic medicines, which employ base-editing. If they eliminated the T cells, the therapy stopped working.

DNA 52
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Ensuring reliable assays: Why the ideal microplate is an invisible one

Drug Discovery World

We find that scientists in early-stage drug discovery are very creative, very innovative and extremely helpful. But it comes with surface charge that will absorb proteins, DNA, and other things, unless you do something to treat that surface. Most importantly, we learned that a microplate should be an invisible carrier of an assay.

Drugs 52