Drug Discovery World

APRIL 4, 2023

Orserdu (elacestrant), Stemline Therapeutics The first and only treatment specifically indicated for patients with ESR1 mutations in ER+, HER2- advanced or metastatic breast cancer was approved in the US in February. This made Jesduvroq is the first oral hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) to be approved in the US.

FDA Approval 52

FDA Approval In-Vivo Gene Editing Drugs 52

Delveinsight

DECEMBER 7, 2020

In May 2020, Freenome initiated AI-EMERGE, a clinical study for the AI-Genomics blood test has been completed, which collected samples from up to 3,000 patients in the US and Canada. The device can be configured to inject a specific dose of the hormones into the patient.

Protein 56

Protein Insulin Hormones FDA Approval 56

Pharmaceutical Technology

MARCH 2, 2023

Keytruda is also indicated for the treatment of patients with recurrent or metastatic squamous cell carcinoma (HNSCC) (as second and first line therapy), in combination with platinum and FU for the first-line treatment of patients with metastatic or with unresectable, recurrent Head And Neck Cancer Squamous Cell Carcinoma (HNSCC), as a single agent (..)

FDA Approval 100

FDA Approval Containment Development Genome 100

The Pharma Data

JULY 23, 2021

1%) as determined by an FDA-approved test, with no EGFR or ALK genomic tumor aberrations. Patients with EGFR or ALK genomic tumor aberrations should have disease progression on FDA-approved therapy for these aberrations prior to receiving OPDIVO. Thyroiditis can present with or without endocrinopathy.

Hormones 52

Hormones Trials Genome Genomics 52

The Pharma Data

MARCH 11, 2021

1%) as determined by an FDA-approved test, with no EGFR or ALK genomic tumor aberrations. Patients with EGFR or ALK genomic tumor aberrations should have disease progression on FDA-approved therapy for these aberrations prior to receiving OPDIVO. Thyroiditis can present with or without endocrinopathy.

Trials 52

Trials Hormones Genome Genomics 52

The Pharma Data

JANUARY 4, 2021

Food and Drug Administration (FDA) , in combination with Tecentriq ® (atezolizumab) for the first-line treatment of people with metastatic non-small cell lung cancer (NSCLC) whose tumors have high PD-L1 expression with no EGFR or ALK genomic tumor aberrations. A type of breast cancer called triple-negative breast cancer (TNBC).

Immune Response 52

Immune Response Medicine Protein Gene 52

The Pharma Data

AUGUST 11, 2020

1%) as determined by an FDA-approved test, with no EGFR or ALK genomic tumor aberrations. Patients with EGFR or ALK genomic tumor aberrations should have disease progression on FDA-approved therapy for these aberrations prior to receiving OPDIVO. Administer hormone-replacement therapy for hypothyroidism.

Trials 52

Trials Hormones Clinical Trials Clinical Trials 52