pharmaphorum

MAY 11, 2022

That was the thinking applied to the formation of Moderna, which paid off spectacularly with its COVID-19 vaccine, used around the world to fight the pandemic, as well as its rapidly expanding pipeline of additional therapeutics. The move follows Novo Nordisk’s $3.3

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Gene Silencing Medicine RNA Licensing 126

pharmaphorum

DECEMBER 23, 2020

It has been a year dominated by the pandemic and many life sciences research projects were put on hold as big pharma turned its attention to vaccines and therapies. But there was some considerable progress in other fields of medicine even though research efforts were diverted away, reports Richard Staines. Rare disease progress.

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Marketing Gene Silencing Gene Drugs 86

Drug Discovery World

OCTOBER 4, 2022

One of the main sessions at this year’s event will look back on how the collaboration between Oxford University and AstraZeneca was crucial to the development and manufacture of their Covid-19 vaccine. Knockout’ mice are bred in a laboratory with specific genes silenced or ‘knocked out’.

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Gene Therapy Drugs Gene Manufacturing 52

Drug Discovery World

AUGUST 1, 2023

As reported by DDW , the aim for the centre is to help future-proof the UK against emerging health threats and the first mRNA vaccine is expected to be produced in the UK in 2025. This Phase I trial will test the experimental vaccine, known as H1ssF-3928 mRNA-LNP, for safety and its ability to induce an immune response.

RNA 52

RNA Drugs Gene Silencing Vaccination 52

Roots Analysis

OCTOBER 22, 2023

RNA interference (RNAi) Therapeutics : Fundamentally, RNAi is a natural process of post-transcriptional gene silencing, involving short strands of nucleic acids. Cells use this process to silence and / or inhibit gene expression, via targeted degradation of specific (unwanted) mRNA molecules.

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RNA Protein Genetics Gene Expression 40