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AGC and RoosterBio partner for cell and exosome therapy manufacturing

Pharmaceutical Technology

Biopharmaceutical contract development and manufacturing organisation (CDMO) AGC Biologics has entered a strategic collaboration with RoosterBio to expedite the manufacturing of cell and exosome therapies. These capabilities comprise cell and exosome genetic engineering for expressing therapeutic targets.

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Enabling the next wave of innovative drug therapies with speciality enzymes

Pharmaceutical Technology

For hundreds of years, we have found myriad uses for microbial enzymes in manufacturing – from food, drink, and household products to a range of industrial applications. For cell and gene therapy applications, you need a variety of speciality enzymes of the highest purity, specificity, and consistency.

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Ginkgo acquires machine learning biotech Patch Biosciences

Drug Discovery World

Ginkgo Bioworks has acquired Patch Biosciences, with the intention to strengthen its gene therapy services, cell therapy services, and RNA therapeutics services. The collaboration achieved its goals of enhancing the AAV production titres of Biogen’s gene therapy manufacturing processes.

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Q&A: A decade on, what’s next for CAR-T therapies?

Pharmaceutical Technology

This approach remains logistically complex, which builds the desire for allogeneic treatments that can be manufactured from unrelated donors on a larger scale. But while companies continue studying allogeneic CAR-T therapies, including for their coveted use in solid tumours, such advancements remain challenging.

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mRNA Cancer Vaccines and Therapies: An Overview

Advarra

Personalized medicine using genetic resequencing techniques, such as cell and gene therapies, enables researchers to create more customized therapies for combatting cancer. Monoclonal Antibodies Monoclonal antibodies are lab-engineered immune system proteins.

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How single-use technologies can improve antibodies production  

Drug Discovery World

mAb production involves extensive, complicated manufacturing operations with many biological raw materials that require detailed procedures and advanced technologies to ensure the quality and stability of the final product. As a result, single-use technologies were explored as a more sustainable approach to mAb manufacturing.

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Overcoming inefficiencies to improve access to cell and gene therapy 

Drug Discovery World

The cell and gene therapy (CGT) landscape has grown significantly in the past year. Between the 24 therapies already approved by the FDA 1 and a marked increase in clinical trials, widespread accessibility to precision medicine feels within reach. Planning—without hoarding resources—is everything.