Remove Genetic Engineering Remove In-Vitro Remove Marketing Remove Regulation
article thumbnail

The evolution of assays for immuno-oncology research

Drug Discovery World

However, over the last few decades, it has been widely accepted that interaction between the tumour and host immune response plays a critical role in regulating tumour biology and hence its progression. The number of new cases recorded between 2016 and 2018 was 375,400, with 167,142 deaths caused by cancer between 2017 and 2019.

article thumbnail

RNA Therapeutics: A Novel Approach to Treating Diseases

Roots Analysis

In the last few years, researchers have become interested in using in vitro transcribed (IVT) mRNA as a drug delivery agent. It is important to highlight that IVT mRNAs are structurally similar to natural mRNAs and can be used to express proteins through genetic engineering.

RNA 40
article thumbnail

Accelerating NDA filing through faster carcinogenicity assessment

Drug Discovery World

This stage is more highly regulated and consists of both preclinical testing and clinical trials. Specific guidelines set forth to regulate these testing processes are issued by the ICH, a non-profit organisation with representation from global regulatory agencies and pharmaceutical companies. billion and take over 10 years.