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Discover how iPSC derived cells can be used to support the development of drug and gene therapies

Drug Discovery World

Primary hepatocytes represent the gold standard in vitro cell model for functionality. This system allows researchers to investigate the effect of the treatment on the target protein, but the cellular environment bears little resemblance to that of the human liver, an impediment to reliable compound triaging.

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How can iPSC derived cells can be used to support drug development?

Drug Discovery World

Primary hepatocytes represent the gold standard in vitro cell model for functionality, however, when isolated from liver tissue, primary cells maintain expression of key proteins for only a short period. In addition, stable cell lines derived from cancers represent a single and karyotypically abnormal genotype.

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Last chance: Discover how iPSC derived cells support drug development

Drug Discovery World

Primary hepatocytes represent the gold standard in vitro cell model for functionality, however, when isolated from liver tissue, primary cells maintain expression of key proteins for only a short period. In addition, stable cell lines derived from cancers represent a single and karyotypically abnormal genotype.

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Register now to discover how iPSC derived cells support gene therapy development

Drug Discovery World

Primary hepatocytes represent the gold standard in vitro cell model for functionality, however, when isolated from liver tissue, primary cells maintain expression of key proteins for only a short period. In addition, stable cell lines derived from cancers represent a single and karyotypically abnormal genotype.

article thumbnail

Using iPSC derived cells for the development of drug and gene therapies

Drug Discovery World

Primary hepatocytes represent the gold standard in vitro cell model for functionality, however, when isolated from liver tissue, primary cells maintain expression of key proteins for only a short period. In addition, stable cell lines derived from cancers represent a single and karyotypically abnormal genotype.

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Nine new industry collaborations driving drug discovery forward

Drug Discovery World

SpyBiotech and the University of Oxford Biotechnology company SpyBiotech and University of Oxford have entered a research agreement for the development of a vaccine against Epstein-Barr virus (EBV). Studies have found that EBV triggers a range of very serious health conditions including certain cancers and multiple sclerosis.

Drugs 52
article thumbnail

Discover how iPSC derived cells can support drug and gene therapy development

Drug Discovery World

Primary hepatocytes represent the gold standard in vitro cell model for functionality, however, when isolated from liver tissue, primary cells maintain expression of key proteins for only a short period. In addition, stable cell lines derived from cancers represent a single and karyotypically abnormal genotype. Watch on demand.