Medical Xpress

FEBRUARY 28, 2023

Using artificial intelligence (AI) methods, researchers led by Professor Dr. Alexander Schönhuth from Bielefeld University's Faculty of Technology have succeeded in recording and deciphering the genotype profiles of 3,000 ALS patients and thus learning more about the development of the disease.

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BioTech 365

JULY 20, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Untrained beer drinkers can taste different barley genotypes.When it comes to craft beer, the flavor doesn’t have to be all in the hops. As a panel of … Continue reading →

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Medical Xpress

MARCH 22, 2023

Fiber intake is associated with a lower risk of developing cognitive decline in those old people with the apolipoprotein E ApoE ε4 genotype, regarded as a genetic risk factor linked to the development of Alzheimer's disease.

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Scienmag

APRIL 19, 2022

New Edith Cowan University (ECU) research has identified a crucial link between arthritis and the risk of serious liver disease in people with Australia’s most common genetic condition.

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Worldwide Clinical Trials

FEBRUARY 6, 2023

The best course of action will depend on many variables, such as the disease or population being studied and the genotype/phenotype relationship, risk, and impact on care. Obtaining appropriate assistance to facilitate planning up front for the complexities involved will save sponsors time and effort in the long run. Read the full article!

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Scienmag

DECEMBER 15, 2020

Striving for a better understanding of pest resistance in experimental lines Credit: Gurjit Singh Tifton, Georgia: A study out of the University of Georgia sought to determine the level of host plant resistance that can be assured by several promising experimental bermudagrass genotypes against potential damages committed by the fall armyworm.

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Drug Discovery World

JANUARY 20, 2023

The massive data sets generated from this research have driven advances in data science and are used to inform additional studies and clinical practice. Standard treatment for some cancers now include genotyping or molecular imaging in living patients.

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Scienmag

AUGUST 25, 2020

Credit: Iliana Baums, Penn State Coral conservation efforts could get a boost from a newly developed genotyping “chip”–the first of its kind for corals.

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pharmaphorum

OCTOBER 9, 2020

We are not aware of so many aspects of this disease because they have not been researched adequately,” she says. Because this disease is so rare and there is no cure yet, it is not seen as important by researchers and physicians. The two research projects, Michelle says, will start to build the evidence base.

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Drug Discovery World

OCTOBER 4, 2022

BioIVT has acquired Fidelis Research, an 85-site clinical biospecimen collection network in Southeastern Europe. . Fidelis Research also possesses cell isolation capabilities and provides custom contract research services for pharmaceutical companies and clinical research organisations (CROs). .

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BioTech 365

JUNE 7, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Sensing what plants sense: Integrated framework helps scientists explain biology and predict crop performance.Scientists have invested great time and effort into making connections between a plant’s genotype, … Continue (..)

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BioTech 365

SEPTEMBER 10, 2020

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: GTEx Consortium releases fresh insights into how DNA differences govern gene expression.Scientists from the Genotype-Tissue Expression (GTEx) project, a National Institutes of Health-funded consortium including researchers from (..)

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pharmaphorum

JANUARY 21, 2022

A third dose of vaccine has been shown to effectively neutralise the Omicron variant of covid-19, according to researchers. Research led by UCLH, UCL and the Francis Crick Institute found that the booster dose successfully stimulates antibody levels that neutralise Omicron. Details of the study were published in The Lancet this week.

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pharmaphorum

JANUARY 16, 2023

Hormone replacement therapy (HRT) could cut the risk of Alzheimer’s in some women at elevated risk of the disease, according to researchers in the UK. Their work specifically focused on the effect of HRT on women with the APOE4 genotype. The research is published in the journal Alzheimer’s Research and Therapy.

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Delveinsight

DECEMBER 13, 2020

Research and development in Hepatitis. However, there is still a need for further research on HCV and the risk factors that lead to the progression of fibrosis, cirrhosis, and Hepatocellular carcinoma (HCC). Typically, pan-genotypic treatments have high cure rates, few side effects, and short treatment durations (usually 8–12 weeks).

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Drug Discovery World

MAY 22, 2023

Not-for-profit medical research organisation LifeArc and techbio company PrecisionLife have agreed a strategic R&D collaboration to accelerate the discovery of targeted treatments for motor neurone disease (MND). LifeArc researchers will lead and coordinate target validation and drug discovery projects.

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pharmaphorum

JULY 13, 2021

The researchers used GPS logging devices and machine learning as “digital biomarkers” to compare the driving of people who have preclinical Alzheimer’s but are still cognitively normal to a control group of normal age-matched drivers over the course of a year.

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The Pharma Data

NOVEMBER 25, 2020

The researchers found that among MCI patients with and without progression to AD, there was no difference in age, gender, or years of education. WEDNESDAY, Nov. 29 to Dec. Of these patients, 72 and 267 progressed to AD and remained stable, respectively.

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The Pharma Data

NOVEMBER 18, 2020

from Cedars-Sinai Medical Center in Los Angeles, and colleagues used whole-exome sequencing and genome-wide genotyping to determine the proportion of 792 IBD patients genetically at risk for TED and investigate the effect of the genetic risk for TED in IBD. The researchers found that 122 of 792 IBD patients (15.4 Takeo Naito, Ph.D.,

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XTalks

MARCH 29, 2021

According to a study by researchers at the National Institutes of Health (NIH), moderate caffeine intake could lead to small babies. The research found that even consumption of less than the recommended moderate amount of 200 mg of caffeine per day for adults, which is about two cups of coffee, posed an increased risk to the fetus.

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The Pharma Data

FEBRUARY 1, 2021

Overall, the researchers found no evidence of an association between EPA plus DHA intake from fish with incident asthma in 4,543 participants. On stratification by FADS genotype, the odds ratio was 0.49 (95 percent confidence interval, 0.31 The potential effect modification by FADS polymorphism (rs1535) was examined.

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Genotype Doctors Doctor Research 52

Advarra

FEBRUARY 28, 2023

In an effort to accelerate the sharing of biomedical research results, the National Institutes of Health (NIH) issued its finalized Data Management and Sharing (DMS) policy , effective January 25, 2023. The policy statement supported reusing existing scientific data and accessibility of high value datasets for use in future research studies.

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Pharmaceutical Technology

DECEMBER 15, 2022

Therefore, there is also a significant need for new therapies that target the underlying cause of CFD that may offer a cure for patients living with severe disease, or for patients with genotypes such as dysfibrinogenemia and hypodysfibrinogenemia, who are often ineligible for treatment with HFCs.

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Roots Analysis

APRIL 28, 2024

However, the rising incidence and prevalence of rare kidney disease, with poor outcomes and high cost has led to an increased research activity in this domain. Diagnosis, management, and treatment of such rare kidney diseases are complicated, especially when multi-system complications are present.

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pharmaphorum

JANUARY 24, 2023

One of the reasons is because researchers now have far more genetic data to work with than was ever previously possible. With such a drop in cost, this means that researchers can test far more often and work with far more genetic data than previously possible. In this way, the company is able to generate drug targets.

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Drug Discovery World

SEPTEMBER 20, 2022

The results were presented at the ME Genetics Research Summit organised by ME charity, Action for ME and the MRC Human Genetics Unit, University of Edinburgh. . The study also identified similarities with genes that are believed to be associated with multiple sclerosis (MS) and long Covid.

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Triage Cancer

JUNE 29, 2021

Tissue Genotyping. Genotype directed therapies. Online communities and how they support, educate and partner with research. This program will cover a wide range of targeted therapy topics and discussions including the following, each of which will immediately be followed by a live Q&A with the audience: . Liquid Biopsies.

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Genotype Doctors Doctor Research 52

XTalks

FEBRUARY 4, 2021

Generation of strong research dataset cohorts must begin with high-quality clinical samples. Moreover, biobanks are no longer passive biorepositories for accrual of samples and serve a more utilitarian function in identifying and coordinating specific research cohorts for longitudinal and prospective studies.

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The Pharma Data

SEPTEMBER 8, 2021

The acquisition enables Roche to further expand the portfolio of currently over 45 CE-IVD assays and more than 100 research use assays on Roche`s LightCycler PCR instruments. TIB Molbiol is a biotech company that has supplied the global market with reagents for research and medical diagnostics for over 30 years. About TIB Molbiol.

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Drug Discovery World

FEBRUARY 27, 2024

Reece A: What are some of the human limitations to current drug discovery research for immunotherapies? Reece A: In pharmaceutical research there is an abundance of data, much of which is untapped. Ron A : One of the bigger challenges is translatability from preclinical work to human studies.

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The Pharma Data

NOVEMBER 2, 2020

ONWARD is investigating Adial’s lead drug candidate, AD04, as a therapeutic agent for the treatment of Alcohol Use Disorder (AUD) in persons with certain target genotypes related to the serotonin transporter and receptor genes. Key ONWARD highlights include: All 25 planned investigative sites are active.

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XTalks

APRIL 29, 2021

Proviral DNA Genotyping. In the HIV space, proviral DNA resistance testing is the newest genotypic resistance testing to be incorporated into the day-to-day management of patients living with HIV, explains Dr. Walworth. Importantly, ARV treatment does not affect the proviral DNA genome that persists in latently infected cells.

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The Pharma Data

MARCH 16, 2022

Roche and its subsidiary, Tib Molbiol, confirm that it has tests for research use that identify the SARS-CoV-2 subvariants of concern, Omicron: BA.1, It’s critical to quickly and accurately identify variants to inform ongoing research – including the ongoing development of therapeutics and vaccines. 3 and Delta.

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XTalks

JANUARY 22, 2021

It identifies bacteria using both genotypic and phenotypic assessments within 1.5 Lee said, “Global research shows that 50 percent usage of antibiotics is inappropriate, and empirical treatment is one of the main causes. Empirical treatment usually gives two to three antibiotics at the same time to suppress unknown bacteria.”.

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The Pharma Data

NOVEMBER 10, 2020

Although a few are out there, phosphorylated tau (P-tau) may enable even earlier and more accurate detection, according to Eli Lilly-associated researchers speaking at the Clinical Trials on Alzheimer’s Disease (CTAD) virtual conference in early November. Tau biomarkers are useful in diagnosing Alzheimer’s disease, these researchers agreed.

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Clinical Trials Clinical Trials Trials Antibody 52

pharmaphorum

NOVEMBER 10, 2021

“Better estimates of the burden of antimicrobial resistance in humans and animals depend on better microbiological data and more clarity on the appropriate design of epidemiological research. This database should support automatic importation from hospitals, laboratories and surveillance networks and link to genotypic data when available.”.

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Drug Discovery World

NOVEMBER 23, 2023

Research that once took months to complete – requiring synthesizing and testing compounds – can now be done in days and even hours using AI.

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