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New research will allow convenient investigation of human innate immune response to viral infections

Scienmag

This new creation makes these cells highly valuable reagents for reporting […].

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Biden Warns of 500,000 COVID Deaths by February

The Pharma Data

The Biden team said it had identified 12 “immediate supply shortfalls” that have been critical to the pandemic response, including N95 surgical masks and isolation gowns, as well as swabs, reagents and pipettes used in testing, the Times reported. ” Both experts stressed that people should still get the vaccine.

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Leveraging flow cytometry in drug discovery 

Drug Discovery World

Accordingly, advances in flow cytometry technology – both in instrumentation and reagent offerings – are enabling researchers to decipher these questions, leading to new discoveries and diagnostic tools. . Reagents produced under ISO certification provide an extra level of traceability to support internal documentation and quality assurance.

Reagent 52
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The importance of glycan analysis and characterisation for biopharma

Drug Discovery World

Furthermore, the sensitivity of the fluorescent label was shown to be around x100 greater than 2-aminobenzamide, a reagent that has been used extensively in the past to label glycans. . The total preparation time for glycan labelling was shortened to less than 10 minutes, which is a significant improvement on alternative methods.

Protein 52
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The evolution of assays for immuno-oncology research

Drug Discovery World

Cancer is a complex heterogenous multistep disease characterised by uncontrolled cell proliferation combined with a dysregulated immune response. A healthy immune system is naturally primed to eliminate malignant and abnormal cells through a synchronised and dynamic interplay between adaptive and innate immunity.

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Delivering on the promise of gene editing

Drug Discovery World

While viral vectors can be highly active, they can lead to only transient expression (rAAV, AdV), can lead to adverse immune responses (AdV) or can integrate randomly into the genome (LV). Each comes with its own drawbacks, including immunogenicity, size restrictions, and off-target effects 6.

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Optimising AAV capsid purification through improved analytics

Drug Discovery World

First, empty capsids may have the potential to induce an elevated immune response to high concentrations of viral particles. This approach, however, can be time-consuming, laborious, and require expensive reagents, including serotype-specific antibodies.