Medical Xpress

DECEMBER 1, 2022

In 2021, a group of scientists led by researchers at the University of North Carolina at Chapel Hill, Weill Cornell Medicine and NewYork-Presbyterian reported that the Moderna mRNA vaccine and a protein-based vaccine candidate containing an adjuvant, a substance that enhances immune responses, elicited durable neutralizing antibody responses to SARS-CoV-2 (..)

Vaccination 75

Vaccination Vaccine Immune Response Containment 75

pharmaphorum

JANUARY 15, 2021

J&J has announced early trial results that suggest its single-shot coronavirus vaccine provides a sustained response against the virus ahead of a phase 3 trial readout due later this month. Both of these vaccines require two doses, as does the most recently approved shot from Moderna, which is due to arrive in the UK in the spring.

Vaccination 119

Vaccination Vaccine Immune Response Antibody 119

Scienmag

JANUARY 18, 2021

Novel tuberculosis vaccine demonstrated strong immune response in mice Credit: University of Sydney Scientists in Australia have developed a method for the rapid synthesis of safe vaccines, an approach that can be used to test vaccine strategies against novel pandemic pathogens such as SARS-CoV-2, the virus that causes COVID-19.

Vaccination 93

Vaccination Vaccine Immune Response Scientist 93

pharmaphorum

NOVEMBER 25, 2022

Scientists in the US say they have developed an mRNA-based vaccine that encompasses all 20 known subtypes of influenza that could form the basis of a future universal jab. The goals of the programme are also similar to those in COVID vaccine development.

Vaccination 105

Vaccination Vaccine Research Immune Response 105

pharmaphorum

JUNE 30, 2021

Just a few months after starting clinical trials of its nasal spray vaccine for COVID-19, US biotech Altimmune is abandoning the project, saying that it generated weaker than expected immune responses in a phase 1 trial. .

Vaccination 98

Vaccination Vaccine Trials Immune Response 98

Drug Discovery World

OCTOBER 31, 2023

The Oxford Vaccine Group at the University of Oxford, UK, has launched the LEGACY03 study into human immunity, aimed to improve the design of seasonal vaccines and allow targeting by age group. As we age, our immune system changes and with it our response to vaccines.

Vaccination 52

Vaccination Vaccine Immune Response Scientist 52

Scienmag

MAY 20, 2021

The findings provide direction for future vaccines or therapies that may offer broader protection against variants LA JOLLA, CA–Fast-spreading variants of the COVID-19-causing coronavirus, SARS-CoV-2, carry mutations that enable the virus to escape some of the immune response created naturally or by vaccination.

Immune Response 40

Immune Response Scientist Vaccination Vaccine 40

The Pharma Data

AUGUST 16, 2021

The study assessed cynomolgus macaques vaccinated with 12µg of either the first or second-generation vaccine candidate. During challenge with the original SARS-CoV-2 virus, animals vaccinated with CV2CoV were found to be better protected based on highly effective clearance of the virus in the lungs and nasal passages.

Immune Response 52

Immune Response Vaccination Vaccine Antibody 52

The Pharma Data

DECEMBER 7, 2020

7, 2020 — Scientists say they may be getting closer to creating a universal flu vaccine. In an early-stage clinical trial with 65 volunteers in the United States, an experimental vaccine triggered strong immune responses to a wide range of flu virus strains and subtypes. MONDAY, Dec.

Scientist 52

Scientist Vaccination Vaccine Immune Response 52

Scienmag

DECEMBER 9, 2020

Phase 2 trials in 1,200 adults, young children, and infants suggest new poliovirus vaccine may have the potential to overcome outbreaks caused by a mutated polio strain linked to the oral vaccine that typically circulates in areas of low immunisation coverage, and poses one of biggest barriers to eradication.

Immune Response 75

Immune Response Vaccination Vaccine Scientist 75

pharmaphorum

NOVEMBER 24, 2020

The developer of Russia’s COVID-19 vaccine Sputnik V has pledged to make it available for less than $10 per dose – or $20 per two-dose course – on the same day as revealing new clinical data with the shot. Pfizer and Moderna’s vaccines require much lower temperatures to prevent their active ingredients from breaking down.

Vaccination 111

Vaccination Vaccine Immune Response Marketing 111

Sciensano

JULY 5, 2023

Vaccin COVID-19 Event type: symposium Audience: general public health professionals journalist PhD students policy makers scientists Description: Sciensano is pleased to invite you to its BelCoVac symposium, which will focus on studies on the COVID vaccine in Belgium.

Vaccination 52

Vaccination Vaccine Immune Response Antibody 52

pharmaphorum

SEPTEMBER 8, 2022

A malaria vaccine developed by members of the University of Oxford team behind the AstraZeneca COVID-19 jab has been hailed as a possible game-changer in the fight against the deadly parasitic infection. g) dose of Novavax’ Matrix-M adjuvant, used to boost the immune response to the R21 antigen. g) or high (50 ?g)

Vaccination 72

Vaccination Vaccine Immune Response Antibody 72

Scienmag

OCTOBER 1, 2020

Identifying potential adjuvants just […].

Vaccination 93

Vaccination Vaccine Immune Response Scientist 93

Scienmag

AUGUST 21, 2020

Nasal delivery produces more widespread immune response than intramuscular injection Credit: Hassan et al. Scientists at Washington University School of Medicine in St.

Vaccination 52

Vaccination Vaccine Immune Response Scientist 52

pharmaphorum

AUGUST 26, 2022

The rivalry between Moderna and Pfizer/BioNTech in commercialising their COVID-19 vaccines has now spilled over into the courts, in the form of a patent infringement lawsuit. ” There’s no world yet on whether a counter-suit may be in the offing. .” Lawsuits sprouting like mushrooms.

Vaccination 59

Vaccination Vaccine Sales Immune Response 59

The Pharma Data

JANUARY 4, 2021

officials ramped up efforts to vaccinate more Americans, scientists around the world wrestled with whether it would make sense to delay the second doses everyone will need so more people can be vaccinated more quickly. Each vaccine would still be delivered in two doses given four weeks apart. MONDAY, Jan.

Scientist 52

Scientist Vaccination Vaccine Immune Response 52

World of DTC Marketing

AUGUST 21, 2020

million people have been infected and over 165,000 have died, the promise of a vaccine is hampered by a vexing epidemic that long preceded Covid-19: obesity. The finding was replicated in a follow-up study that used longer needles to ensure the vaccine was injected into muscle and not fat. In the United States, where at least 4.6

Immune Response 238

Immune Response Vaccination Vaccine Scientist 238

pharmaphorum

JULY 12, 2022

Researchers in the US have started a clinical trial of a vaccine against Nipah virus, a serious infection caught from animals that has a fatality rate of between 40% and 70%, developed by mRNA specialist Moderna. “The need for a preventive Nipah virus vaccine is significant,” he added. .

Vaccination 52

Vaccination Vaccine Trials Immune Response 52

World of DTC Marketing

APRIL 11, 2021

QUICK THOUGHT: People believe the COVID-19 vaccine was developed in less than a year but that’s not true. Based on the virus a number of vaccines targeting the spike protein were designed, tested in animal models and found to be quite promising against SARS and other coronavirus illnesses like Middle East respiratory syndrome.

Vaccination 303

Vaccination Vaccine Clinical Trials Clinical Trials 303

XTalks

JULY 14, 2021

In a press briefing on Monday, the World Health Organization (WHO) responded to questions about COVID-19 vaccine boosters that led to a flurry of misleading headlines in the media about the “dangers” of mixing and matching vaccines. Related: Disinformation Dozen: The Anti-Vaxxers Behind Most Social Media Misinformation.

Vaccination 98

Vaccination Vaccine Immune Response FDA Approval 98

STAT News

OCTOBER 19, 2022

… Moderna disclosed that its Covid-19 vaccine booster targeting the BA.1 1 subvariant of Omicron generated a strong immune response against that variant, with antibody levels staying high for at least three months , Reuters notes. Omicron-tailored 5 targeted vaccine later this year. 5 subvariants of Omicron.

Immune Response 98

Immune Response Scientist Vaccination Vaccine 98

The Pharma Data

NOVEMBER 10, 2021

Next generation vaccines for COVID-19 should aim to induce an immune response against ‘replication proteins’, essential for the very earliest stages of the viral cycle, concludes new research carried out by UCL scientists. ” Discovering the T cell response to replication proteins. .”

Vaccination 52

Vaccination Vaccine Immune Response Protein 52

The Pharma Data

NOVEMBER 16, 2020

16, 2020 — Scientists are reporting early success with an experimental herpes vaccine that uses a genetically modified version of the virus. The gene edit prevents the virus from performing its normal evasive maneuver: hiding out in nervous system cells in order to elude the immune system. MONDAY, Nov.

Vaccination 52

Vaccination Vaccine Immune Response Genetics 52

The Pharma Data

AUGUST 9, 2021

Research by Lancaster University scientists to create a COVID-19 vaccine which can be administered through the nose has taken a significant step forward. The pre-clinical animal trials of the intranasal vaccine showed a reduction in both the impact of the disease itself and transmission of the virus.

Vaccination 52

Vaccination Vaccine Immune Response Scientist 52

pharmaphorum

SEPTEMBER 29, 2020

Inovio Pharma’s plan to start pivotal testing of its COVID-19 vaccine has been delayed by FDA requests for more information, sending its shares into a swift decline. Inovio’s vaccine takes the form of a DNA plasmid coding for the full length of the spike or ‘s’ glycoprotein antigen of SARS-CoV-2, the vaccine that causes COVID-19.

Vaccination 52

Vaccination Vaccine Trials DNA 52

Medical Xpress

MARCH 28, 2023

A team of scientists from the Renaissance School of Medicine (RSOM) at Stony Brook University has identified a distinct role of retinoic acid, a metabolite of vitamin A, during the immune response of the gut.

Immune Response 75

Immune Response Scientist Medicine Vaccination 75

The Pharma Data

OCTOBER 18, 2021

Northwestern Medicine scientists have shown for the first time that coronavirus vaccines and prior coronavirus infections can provide broad immunity against other, similar coronaviruses. The findings build a rationale for universal coronavirus vaccines that could prove useful in the face of future epidemics.

Vaccination 40

Vaccination Vaccine Immune Response Antibody 40

The Pharma Data

JANUARY 22, 2021

As research developments into RNA vaccines help scientists accelerate drug candidates to arm the immune system against coronavirus, Pharma IQ ’s Keeping tabs on Covid-19 update returns with news from some of the biotechnology innovators leading the fight against the global pandemic.

Vaccination 52

Vaccination Vaccine Protein Immune Response 52

The Pharma Data

SEPTEMBER 30, 2021

An expert review by a world group of scientists, including some at the WHO and FDA, concludes that, even for the delta variant, vaccine efficacy against severe COVID is so high that booster doses for the overall population aren’t appropriate at this stage within the pandemic.

Vaccination 52

Vaccination Vaccine Antibody Immune Response 52

The Pharma Data

AUGUST 15, 2021

Even as several safe and effective COVID-19 vaccines are being administered to people worldwide, scientists are still hard at work developing different vaccine strategies that could provide even stronger or longer-lasting immunity against SARS-CoV-2 and its variants.

Protein 52

Protein Vaccination Vaccine Antibody 52

Drug Discovery World

JANUARY 12, 2024

The top stories: Excitement over new antibiotics that can kill drug-resistant bacteria A novel antibiotic class targeting a major global pathogen and threat to human health has been discovered by scientists from Roche and Harvard University (Cambridge, MA, US).

Drugs 52

Drugs Immune Response Allergies Bacteria 52

pharmaphorum

JULY 14, 2021

AstraZeneca and Johnson & Johnson are both exploring ways to modify their COVID-19 vaccines to minimise the risk of severe blood clotting reactions that are seen – albeit rarely – in some people receiving the jabs. Its guideline is due to be published before the end of this month.

Vaccination 116

Vaccination Vaccine Immune Response Protein 116

The Pharma Data

AUGUST 27, 2020

A new effort is under way to understand how the immune system responds to coronavirus. Scientists from 17 UK research centres are attempting to answer questions such as how long immunity lasts and why disease severity varies so much. The immune system is underlying everything that’s key to the response to this virus.”.

Scientist 52

Scientist Immune Response Research Vaccination 52

The Pharma Data

JANUARY 5, 2021

Food and Drug Administration said Monday that any American who gets the Moderna or Pfizer coronavirus vaccines must get two full doses, despite international debate on possible ways to stretch vaccine supply. vaccine effort just as the public is starting to trust the program, Dr. Anthony Fauci told The New York Times.

Vaccination 52

Vaccination Vaccine Immune Response Trials 52

pharmaphorum

JANUARY 6, 2023

The UK has formed an partnership with German biotech BioNTech to provide up to 10,000 patients with access to personalised cancer therapies, in another example of the country embracing the mRNA technologies that underpinned COVID-19 vaccines. It will also cover some infectious disease targets.

Clinical Trials 111

Clinical Trials Clinical Trials Trials Vaccination 111

pharmaphorum

DECEMBER 11, 2020

Sanofi and GlaxoSmithKline have said their COVID-19 vaccine has hit a snag in clinical development, prompting analysts to note this could delay delivery of potentially more than a billion shots globally by up to nine months. AZ to combine vaccine with Russian rival.

Immune Response 72

Immune Response Trials Vaccination Vaccine 72