Drug Discovery World

APRIL 3, 2023

As a business of scientists, we remain passionate about the exciting developments in the industry, from research to precision therapies, and insatiably curious about the new possibilities that can be achieved by overcoming the limits of standard research tools and methods. DDW’s Diana Spencer caught up with co-founder and CEO Dr Arron Tolley.

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Antibody Gene Therapy Gene In-Vitro 52

XTalks

APRIL 22, 2022

Receptor occupancy assays have been developed and applied in both nonclinical and clinical studies to provide insight into PK/PD relationships so far,” said Andre Olsson, PhD, Senior Scientist, Flow Cytometry at the global contract research organization (CRO) Medpace. What is Flow Cytometry?

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Clinical Trials Clinical Trials Trials Antibody 98

Drug Discovery World

NOVEMBER 30, 2023

This presentation covered three primary drivers for a protein expression model: speed, cost and sustainability. “It The next presentation attended in this track was the keynote presentation, which was given by Kate Smith, PhD, Head of UK Protein & Cell Sciences at GSK. GSK has developed high-throughput mammalian and E.

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Antibody Protein Engineer In-Vivo 59

Drug Discovery World

DECEMBER 13, 2023

Moreover, custom antibodies are a key reagent in companion diagnostics for these novel therapeutics. Custom antibodies can be developed for pharmacokinetic assays and biodistribution assays, supporting therapeutic development by giving researchers data about the behaviour of their novel therapeutic in vivo.

Life Science 59

Life Science Antibody Manufacturing In-Vivo 59

Drug Discovery World

JULY 18, 2023

Current research is focused on designing CRISPR-enhanced CAR T cells that are resistant to immunosuppressive cytokines such as transforming growth factor-β (TGF-β) 2 , programmed cell death protein (PD-1) 3 , or other negative T cell regulators 4 (CTLA-4, LAG-3, and TIM-3), thus improving anti-tumour functions.

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DNA Genome Genomics RNA 98

Drug Discovery World

OCTOBER 20, 2022

Dr Amber Miller, Flow Cytometry Scientist, Fortis Life Sciences, says flow cytometry techniques can help our understanding of cancer associated fibroblasts but there is still work to be done. Fibroblasts in the tumour microenvironment. Cancer associated fibroblasts (CAFs) have recently emerged as key players in the tumour microenvironment.

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Antibody In-Vivo Life Science Development 52