Clinical Research Informer

Grand Rounds November 17, 2023: Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications: Results from the Nudge Study (Michael Ho, MD, PhD; Sheana Bull, PhD)

Rethinking Clinical Trials

NOVEMBER 21, 2023

The Nudge study wanted to find out if nudges could help patients improve medication adherence by promoting behavioral change through positive reinforcement. Text messages can be implemented as a low-cost intervention to improve medication refill adherence across different healthcare systems with disperate EHR systems.

Clinical Trials

Clinical Trials Clinical Trials Trials Development

Grand Rounds December 2, 2022: A Randomized Controlled Trial of Mobile Health Intervention in Heart Failure and Diabetes: Lessons Learned (G. Michael Felker, MD, MHS)

Rethinking Clinical Trials

DECEMBER 6, 2022

Medication adherence can be a barrier to effectiveness. The focus of the study was on physical activity and medication adherence. Secondary endpoints were change in medication adherence, change in HRQOL, change in NT-proBNP, and change in hemoglobin A1C from baseline to 3 months. Key Points. Discussion Themes.

Trials

Trials Clinical Trials Clinical Trials Compliance

Grand Rounds February 23, 2024: Virtual Vigilance: Monitoring of Decentralized Clinical Trials (Adrian Hernandez, MD; Christopher J. Lindsell, PhD)

Rethinking Clinical Trials

FEBRUARY 28, 2024

It is based on good study design and focusing on the key principles we are trying to adhere to. Tags #pctGR, @Collaboratory1 The post Grand Rounds February 23, 2024: Virtual Vigilance: Monitoring of Decentralized Clinical Trials (Adrian Hernandez, MD; Christopher J. There has to be a range of approaches that could be fit for use.

Clinical Trials

Clinical Trials Clinical Trials Trials Clinical Research

BD partners with Biocorp on connected self-injection devices

pharmaphorum

OCTOBER 18, 2022

Medtech giant Beckton Dickinson (BD) has signed a deal with France’s Biocorp to use the latter’s near-field communication (NFC) tags in injectable devices. The Injay tag can confirm a complete injection and transfer that information via an NFC reader to a smartphone or tablet for review by a healthcare professional.

Drug Delivery

Drug Delivery Manufacturing Drugs Marketing

Jolly Good/Teijin Pharma develop VR digital therapeutics for depression

pharmaphorum

APRIL 26, 2021

In 2019 Cognitant and Addenbrook’s Hospital in Cambridge, UK piloted a programme that aimed to educate patients to improve adherence to rheumatoid arthritis medicines. Virtual reality is a technology that is beginning to be used in healthcare across a variety of settings.

Development

Development Medicine Production Marketing

Patient adherence – the key to restoring trust in pharma

pharmaphorum

JANUARY 31, 2023

This lack of trust in such a crucial industry can lead to decreased compliance, poor treatment adherence, and negative health outcomes for patients. This discrepancy can be caused by a variety of factors, however, one of the primary and most solvable ones is patient non-adherence to their medications.

Clinical Trials

Clinical Trials Clinical Trials Trials Vaccination

Grand Rounds May 19, 2023: Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis After a Fracture (Robert O’Toole, MD)

Rethinking Clinical Trials

MAY 25, 2023

A pilot study, called the ADAPT trial, demonstrated feasibility, similar in-patient compliance and similar post-discharge adherence for the 2 options. Researchers aimed to test the safety and effectiveness of Aspirin use as prophylaxis in orthopedic trauma cases.

Trials

Trials Clinical Trials Clinical Trials Compliance

Grand Rounds May 5, 2023: All of Us Research Program: Improving Health Through Diverse Technology, Huge Cohorts, and Precision Medicine (Joshua C. Denny, MD, MS)

Rethinking Clinical Trials

MAY 10, 2023

We want trials to adhere to our core values and have the data come back to our ecosystem. Tags #pctGR, @Collaboratory1 The post Grand Rounds May 5, 2023: All of Us Research Program: Improving Health Through Diverse Technology, Huge Cohorts, and Precision Medicine (Joshua C. We are not at the capability yet where we can open this up.

Medicine

Medicine Research Clinical Trials Clinical Trials

Grand Rounds Ethics and Regulatory Series February 10, 2023: Informing and Consenting: What Are the Goals? (P. Pearl O’Rourke, MD; David S. Wendler, PhD, MA; Miguel Vazquez, MD; P. Michael Ho, MD, PhD)

Rethinking Clinical Trials

FEBRUARY 16, 2023

The Nudge Study is a pragmatic clinical trial seeking to improve medication adherence to patients’ already-prescribed cardiovascular medications through a series of theory-based text or voice messages that served as “nudges.” Opt-outs were different across health systems. Pearl O’Rourke, MD; David S.

Clinical Trials

Clinical Trials Clinical Trials Medicine Trials

NICE reaches a deal with Roche on access to oral SMA drug Evrysdi

pharmaphorum

NOVEMBER 19, 2021

million price tag make it is the most expensive treatment ever approved for NHS funding. Zolgensma meanwhile has been recommended for some babies aged up to 2 months with type 1 SMA and for treating pre-symptomatic SMA, even though the gene therapy’s £1.79

Drugs

Drugs Gene Therapy Genetic Disease Gene

Grand Rounds October 21, 2022: Disinformation, Cyberthreat, and Choice: Protecting Patients and Clinical Research From the Digital Triple Threat (Eric Perakslis, PhD; Andrea Downing)

Rethinking Clinical Trials

OCTOBER 27, 2022

Three out of 5 companies included in the study were not adhering to their privacy policies. In a recent paper, Health advertising on Facebook: Privacy and Policy Considerations, patients download their raw data, and found who was tracking them across the internet. pctGR, @Collaboratory1.

Clinical Research

Clinical Research Research Clinical Trials Clinical Trials

Grand Rounds March 17, 2023: Remote Symptom Monitoring with Electronic Patient-Reported Outcomes (ePROs) in Oncology (Ethan Basch, MD, MSc)

Rethinking Clinical Trials

MARCH 21, 2023

In this study adherence with week ePROs was 91.5%. Tags #pctGR, @Collaboratory1 The post Grand Rounds March 17, 2023: Remote Symptom Monitoring with Electronic Patient-Reported Outcomes (ePROs) in Oncology (Ethan Basch, MD, MSc) appeared first on Rethinking Clinical Trials. You will want a dedicated tool for adverse events.

Clinical Trials

Clinical Trials Clinical Trials Trials Research

Grand Rounds Ethics and Regulatory Series October 14, 2022: Responding (or Not) to Signals of Potential Clinical Significance in Pragmatic Clinical Trials (Joseph Ali, JD; Tanya Matthews, PhD; Leslie J. Crofford, MD)

Rethinking Clinical Trials

OCTOBER 19, 2022

The timeliness of the response is also important; if the trial is monitoring something they need to be able to respond timely. In the second example, they were not able to. The context of the trial matters a lot in addition to actionability. pctGR, @Collaboratory1.

Clinical Trials

Clinical Trials Clinical Trials Trials Medicine

Salesforce Platform Capabilities

Cloudbyz

JUNE 1, 2023

They also adhere to local data protection and privacy laws, such as GDPR in Europe. Comprehensive Compliance Salesforce offers a comprehensive suite of compliance features to ensure data privacy, security, and adherence to various industry regulations. Users can also collaborate on files, add comments, and tag colleagues.

Compliance

Compliance Development Branding Production

Grand Rounds June 9, 2023: Emulating Randomized Clinical Trials with Non-randomized Real-world Evidence Studies: Results From The RCT DUPLICATE Initiative (Shirley V. Wang, PhD)

Rethinking Clinical Trials

JUNE 14, 2023

Tags #pctGR, @Collaboratory1 The post Grand Rounds June 9, 2023: Emulating Randomized Clinical Trials with Non-randomized Real-world Evidence Studies: Results From The RCT DUPLICATE Initiative (Shirley V. It’s a great approach to directly compare the parameters to see what question you’re truly asking.

Clinical Trials

Clinical Trials Clinical Trials Trials Research

PentagonFit Fitness Tracker

The Pharma Data

MAY 15, 2021

Web Beacons are tags that can monitor the behavior of a user visiting the Website or sending an e-mail. The Company instructs our employees with access to your information that it is to be used only in adherence with the principles set forth in this Privacy Policy and the applicable laws.

Production

Production Containment Medicine Vaccination

Clinical Research Informer

Grand Rounds November 17, 2023: Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications: Results from the Nudge Study (Michael Ho, MD, PhD; Sheana Bull, PhD)

Grand Rounds December 2, 2022: A Randomized Controlled Trial of Mobile Health Intervention in Heart Failure and Diabetes: Lessons Learned (G. Michael Felker, MD, MHS)

Trending Sources

Grand Rounds February 23, 2024: Virtual Vigilance: Monitoring of Decentralized Clinical Trials (Adrian Hernandez, MD; Christopher J. Lindsell, PhD)

BD partners with Biocorp on connected self-injection devices

Jolly Good/Teijin Pharma develop VR digital therapeutics for depression

Patient adherence – the key to restoring trust in pharma

Grand Rounds May 19, 2023: Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis After a Fracture (Robert O’Toole, MD)

Grand Rounds May 5, 2023: All of Us Research Program: Improving Health Through Diverse Technology, Huge Cohorts, and Precision Medicine (Joshua C. Denny, MD, MS)

Grand Rounds Ethics and Regulatory Series February 10, 2023: Informing and Consenting: What Are the Goals? (P. Pearl O’Rourke, MD; David S. Wendler, PhD, MA; Miguel Vazquez, MD; P. Michael Ho, MD, PhD)

NICE reaches a deal with Roche on access to oral SMA drug Evrysdi

Grand Rounds October 21, 2022: Disinformation, Cyberthreat, and Choice: Protecting Patients and Clinical Research From the Digital Triple Threat (Eric Perakslis, PhD; Andrea Downing)

Grand Rounds March 17, 2023: Remote Symptom Monitoring with Electronic Patient-Reported Outcomes (ePROs) in Oncology (Ethan Basch, MD, MSc)

Grand Rounds Ethics and Regulatory Series October 14, 2022: Responding (or Not) to Signals of Potential Clinical Significance in Pragmatic Clinical Trials (Joseph Ali, JD; Tanya Matthews, PhD; Leslie J. Crofford, MD)

Salesforce Platform Capabilities

Grand Rounds June 9, 2023: Emulating Randomized Clinical Trials with Non-randomized Real-world Evidence Studies: Results From The RCT DUPLICATE Initiative (Shirley V. Wang, PhD)

PentagonFit Fitness Tracker

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