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Enhertu gets breakthrough tag in HER2-low breast cancer

pharmaphorum

AstraZeneca and Daiichi Sankyo have claimed a fifth breakthrough designation from the FDA for Enhertu, shortly after showing the drug extended survival in patients with HER2-low metastatic breast cancer. The post Enhertu gets breakthrough tag in HER2-low breast cancer appeared first on.

Sales 58
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Pfizer and Arvinas win UK’s fast track tag for breast cancer drug

Pharmaceutical Technology

Vepdegestrant was awarded the Innovation Passport designation for treating advanced or metastatic breast cancer.

Drugs 130
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Gilead tags Merck for first-line triple negative breast cancer trial

pharmaphorum

Take two recently-approved immunotherapies for triple negative breast cancer (TNBC), put them together, and what do you get? “This helps further our ambition of displacing chemotherapy with Trodelvy to improve outcomes for people living with cancer,” said Gilead’s chief medical officer Merdad Parsey.

Trials 52
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AROMATASE INHIBITORS IN BREAST CANCER

Pharma Tutor

AROMATASE INHIBITORS IN BREAST CANCER. Read more about AROMATASE INHIBITORS IN BREAST CANCER Log in or register to post comments Read more about AROMATASE INHIBITORS IN BREAST CANCER Log in or register to post comments About Authors. MANISHA KOTADIYA*, JAYDEEP SAVALIYA. DOWNLOAD AS PDF.

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Epigenetics discovery could lead to new class of cancer drugs

Drug Discovery World

A new paper has solved the 20-year mystery of how epigenetic modifications act as traffic lights to control gene expression and could ultimately speed up the development of a new class of epigenetic cancer drugs. Epigenetics is still largely unexplored and referred to as the ‘dark matter’ of the genome.

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Blue Note leukaemia DTx gets FDA breakthrough tag

pharmaphorum

It has since been joined by other products in the software as a medical device (SaaMD) category, including Pear Therapeutics’ alcohol-use disorder candidate Pear-009 and another Blue Note DTx, codenamed BNT001, which is also being tested for anxiety and depression in cancer patients.

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FDA gives Daiichi Sankyo’s HER3 drug a breakthrough tag

pharmaphorum

Daiichi Sankyo has been granted breakthrough status by the FDA for patritumab deruxtecan, a HER3-targeted antibody-drug conjugate (ADC) in clinical trials for lung cancer. The post FDA gives Daiichi Sankyo’s HER3 drug a breakthrough tag appeared first on. Daiichi Sankyo and AZ are close collaborators in the ADC arena.

Drugs 71