Remove tag good-therapeutics
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Jolly Good/Teijin Pharma develop VR digital therapeutics for depression

pharmaphorum

Technology firm Jolly Good and Teijin Pharma have begun a partnership to develop virtual reality digital therapeutics (VR DTx) for major depressive disorder. Jolly Good has already won a “Home Healthcare Award” in a programme held by Teijin in December last year.

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Grand Rounds July 15, 2022: Overview of Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) Public-Private Partnership and Lessons Learned (Stacey J. Adam, PhD)

Rethinking Clinical Trials

There were four ACTIV fast-track focus areas: vaccines, preclinical, clinical trial capacity, and therapeutics – clinical. In the therapeutics arm, the most promising therapeutic agents for COVID-19 were prioritized. The team reviewed 800 candidates over 2 years time. We selected 35 and completed testing of 27 of them.

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Grand Rounds Ethics and Regulatory Series December 9, 2022: The Stepped Wedge Cluster Randomized Trial: Friend or Foe? (Monica Taljaard, PhD; David Magnus, PhD)

Rethinking Clinical Trials

There are several good reasons to adopt a cluster randomization trial, including that the intervention is a cluster-level intervention or the research question of interest pertains to cluster-level effects. – Could stepped wedge be a good design for implementation trials? pctGR, @Collaboratory1.

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Perfusion MRI and Other Perfusion Imaging Techniques for Clinical Trials

XTalks

However, the role of MRI in new drug clinical trials can involve diagnosis of lesions and determination of their severity, early identification of therapeutic responders to drug treatment and treatment monitoring and follow-up. For most of this time, MRI mainly was used for qualitative interpretation and simple structural measurements.

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After a slow start for expensive CAR-T therapies, drug developers revisit oral therapies for blood cancer

pharmaphorum

price tag of $475,000 when it was first launched in 2017 – and it becomes apparent that these may not be desirable treatment options for every patient and in every setting. Add to this the considerable cost of these medications – the first approved CAR-T, Novartis’ Kymriah (tisagenlecleucel), had a U.S.

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No sign of stopping: The rise of cell and gene therapy

Drug Discovery World

But are these price tags a barrier to access? You could thus infer that in some cancers, CAR-T treatment may be the great equaliser, which is why access should be more widespread and costs of goods, and eventually cost of drugs, must be brought down. million per dose.

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Grand Rounds January 19, 2024: Why Are Imaging RCTs Different? Lessons From Chest Pain Evaluation Trials (Pamela S. Douglas, MD, MACC, FASE, FAHA)

Rethinking Clinical Trials

RCT design will vary depending on which CAD manifestation(s) are reflected in the information provided by the imaging test being studied, which affects the treatment target(s) being evaluated in a therapeutic trial. There is no single CAD phenotype that can be targeted diagnostically or therapeutically. They are pretty good.

Trials 159