tag mrna 
Drug Discovery World
JULY 25, 2023
DDW recently hosted Where are the breakthroughs in mRNA drug discovery and development? In this webinar, sponsored by Elegen, attendees learnt about the breakthroughs in mRNA drug discovery and development. We have shown that the excipient does not only work for our SNAP-tag lipid (SNaP) LNP, but also for the commercialised vaccines.
XTalks
OCTOBER 26, 2021
The treatment came with an initial price tag of $39,000 per vial, which amounts to a total of $575,00 each year. Givlaari reduces ALAS1 levels through RNA interference-mediated gene silencing, which targets ALAS1 mRNA. However, Alnylam recently offered a confidential discount just before NICE’s latest recommendation came out.
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pharmaphorum
NOVEMBER 19, 2021
The mRNA jab, developed by Pfizer and BioNTech, launched to huge fanfare in December 2020 and promised the start of the end of the coronavirus pandemic. Together, these mRNA jabs have an iron grip on the covid vaccine market – in the US, they have consolidated a 90% market share. Katrina Megget reports. per dose in the US and €19.50
XTalks
MARCH 22, 2023
Top-Selling Drugs by Year It’s no surprise that the best-selling drug of 2022 was Pfizer/BioNTech’s COVID-19 vaccine, Comirnaty (COVID-19 vaccine, mRNA). In addition, nearly half of all new drugs launched between 2020 and 2021 came with a price tag of $150,000 per year, or more. Click on the infographic to explore the data.
Drug Discovery World
OCTOBER 28, 2022
Could mRNA become a ‘universal’ Covid-19 treatment? . Click’ chemistry used to tag proteins made by cancer cells . This week’s top stories: . New research suggests messenger RNA can be effectively used as a ‘universal’ therapy against different coronaviruses. . Radioactive implant ‘completely eliminated’ tumours .
Drug Discovery World
NOVEMBER 13, 2023
These topics include: subcutaneous administration and immunogenicity risk- current understanding and future considerations including novel modalities; and challenges and outlook of mRNA delivery and formulation. Opher Gileadi, PhD, Head, Protein Science SGC, Karolinska Institute, on: ‘Targeting every human protein: Challenges and prospects’.
Drug Discovery World
NOVEMBER 9, 2023
Esperanza Rivera de Torre, PhD, Assistant Professor, Center for Antibody Technologies, Department of Bioengineering, Technical University of Denmark, on: ‘Venom on demand: optimising snake toxin yield, folding, and purity in E coli and P pastoris with biotinylation, solubility, and purification tags’.
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