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Immune cells research could lead to personalised cancer treatments  

Drug Discovery World

Immune B cells could be used to develop cancer targeting immunotherapies, following new research by scientists at The Institute of Cancer Research, London, the University of Oxford and University of Cambridge. B cells are similar to T cell in that they work as part of the immune system to help fight infections as well as cancer.

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XBB.1.5 Omicron Subvariant Being Closely Watched as Most Transmissible Variant Yet

XTalks

It also seems to be very adept at evading the immune response owing to a plethora of mutations that makes it immune evasive. “It The new subvariant has also been dubbed “Kraken” by some scientists. on the horizon as scientists say the virus appears to be rapidly evolving , mutating faster than most viruses.

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2023 cancer research highlights: Drug development at its best

Drug Discovery World

Scientists have used CRISPR gene editing to target and rapidly destroy glioblastoma cells in an approach that could apply to other highly mutated cancers. In glioblastoma, as with many other highly recurrent cancers, tumour cells that escape treatment develop multiple genetic adaptations that allow them to proliferate.

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South African variant may cut response from Pfizer/BioNTech shot, study finds

pharmaphorum

Researchers from the University of Texas Medical Branch based their findings on lab tests using SARS-CoV-2 coronaviruses that were genetically engineered to have the same mutations as those in the strain that is causing scientists so much concern.

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Mutations leading to omicron variant did not enable virus to fully escape immune system

The Pharma Data

People who gained immunity – either through vaccination or exposure – against the original strain of SARS-CoV-2, the virus that causes COVID-19, also are likely to have some protection against the pathogen’s omicron variant. The samples were stored after the researchers measured the T cell response. population.

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Regeneron Announces Encouraging Initial Data from COVID-19 Antibody Cocktail Trial in Hospitalized Patients on Low-flow Oxygen

The Pharma Data

As in earlier outpatient trial, immune status when patients entered the trial was a strong predictor of viral load and clinical outcomes. First antibody therapy to demonstrate anti-viral effect in patients hospitalized with COVID-19. Regeneron Pharmaceuticals, Inc. futility analysis). The results passed the futility analysis (p<0.3

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BioNTech to deliver prestigious lecture on mRNA  

Drug Discovery World

The talk will cover the technology behind the vaccine and the mechanisms of antibody and T cell immune responses triggered by the Covid-19 mRNA vaccine. . The lecture is one of a series of named lectures, organised by the LMB and given by eminent scientists from around the world. . Lecture abstract: .