Remove Bacteria Remove Contamination Remove Manufacturing Remove Protein
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10 of the Worst Food Safety Scandals in Recent History

XTalks

The causes of these events varied, from contaminated food and water to zoonotic diseases and poor hygiene practices. It was caused by contaminated ice cream products manufactured by Blue Bell Creameries, a popular ice cream company based in Texas. coli O157:H7 bacteria.

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Biopharmaceutical Filtration: A Deep Dive

Roots Analysis

Biopharmaceutical filtration is a critical step in the production of biopharmaceuticals, including proteins, antibodies, and vaccines. It involves the separation of unwanted particles from biological materials to obtain contaminant free products. For example, ultrafiltration retains proteins, allowing other molecules to pass through.

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Cell culture Q&A: Solving biomanufacturing challenges with Recombinant Insulin supplementation

Pharmaceutical Technology

In addition to revolutionising diabetes care, insulin has become an essential component of biopharmaceutical manufacturing, where its growth-supplementing ­­­properties are relied on to enhance commercially available cell culture media and achieve higher yields of target therapeutic proteins. One big challenge is contamination.

Insulin 130
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Advances in cell line development

Drug Discovery World

Cell line development is an essential underpinning of the drug development process, enabling teams to test, optimise and manufacture therapeutics at a commercial scale. For instance, bacteria and yeast cell lines are easier to cultivate compared with mammalian cell lines, requiring less maintenance for the medium they are grown in.

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Improving quality control for CAR T cell therapies

Drug Discovery World

And as researchers study all of these factors, they are also discovering that CAR T cell development and manufacturing require a new approach to quality control to ensure their safety and efficacy. To overcome this evasion tactic, the CAR protein was developed to recognise other markers on cancer cells.