Roots Analysis

FEBRUARY 27, 2024

The firm also has the right to obtain exclusive licenses to the Affimer proteins for clinical development and commercialization. What are Affimers : Affimers are small proteins that target and bind molecules on cellular surfaces in a manner analogous to monoclonal antibodies.

Antibody 52

Antibody Licensing Licensing Contract Manufacturing 52

Roots Analysis

OCTOBER 16, 2023

Biopharmaceutical filtration is a critical step in the production of biopharmaceuticals, including proteins, antibodies, and vaccines. Membrane Filters: Membrane filters are typically used for sterilization and removal of smaller impurities such as bacteria and viruses. are used to remove any residual bacteria, viruses, or endotoxins.

Bacteria 40

Bacteria Production Contamination Protein 40

Drug Discovery World

APRIL 30, 2024

Its job is to carry coding information that is essential to the translation and processing of functional proteins. This is essential to its use as a therapeutic agent and gives the technology a vast versatility making it suitable to treating a wide range of diseases – especially those that have high protein expression.

RNA 52

RNA Protein Vaccination Vaccine 52

pharmaphorum

DECEMBER 15, 2020

Proceeds will advance the clinical development of MinervaX’s novel GBS vaccine through phase 2 clinical trials, as well as manufacturing and regulatory preparation for phase 3. These are capable of mobilising the immune system against GBS bacteria and preventing invasion of epithelial and endothelial cell barriers.

Bacteria 52

Bacteria Vaccination Vaccine Immune Response 52

Pharmaceutical Technology

MAY 17, 2023

In addition to revolutionising diabetes care, insulin has become an essential component of biopharmaceutical manufacturing, where its growth-supplementing ­­­properties are relied on to enhance commercially available cell culture media and achieve higher yields of target therapeutic proteins.

Insulin 130

Insulin Production Manufacturing Contamination 130

Drug Discovery World

AUGUST 10, 2022

And as researchers study all of these factors, they are also discovering that CAR T cell development and manufacturing require a new approach to quality control to ensure their safety and efficacy. To overcome this evasion tactic, the CAR protein was developed to recognise other markers on cancer cells.

Manufacturing 98

Manufacturing Gene Genome Genomics 98

The Pharma Data

APRIL 26, 2022

This investigational multivalent protein subunit vaccine uses an established mechanism of action for a Lyme disease vaccine that targets the outer surface protein A (OspA) of Borrelia burgdorferi, the bacteria that cause Lyme disease. About VLA15 VLA15 is the only Lyme disease vaccine candidate currently in clinical development.

Vaccination 52

Vaccination Vaccine Bacteria Protein 52

The Pharma Data

APRIL 22, 2023

Plasma cells produce antibodies that protect the body from invasive foreign substances, such as bacteria and viruses. When transforming into cancerous myeloma cells, however, plasma cells continue to produce monoclonal immunoglobulin (M protein) that is not capable of attacking the foreign substances.

Antibody 40

Antibody Protein Bacteria Drugs 40

Roots Analysis

OCTOBER 16, 2023

Once isolated, molecular clones can be used to generate multiple copies of DNA for the analysis of gene sequences and / or to express proteins obtained for the study or utilization of protein function. These clones can be manipulated and mutated in vitro to alter the expression and function of a protein.

DNA 40

DNA Gene Protein In-Vitro 40

Pfizer

FEBRUARY 16, 2023

This investigational multivalent protein subunit vaccine uses an established mechanism of action for a Lyme disease vaccine that targets the outer surface protein A (OspA) of Borrelia burgdorferi, the bacteria that cause Lyme disease. OspA is a surface protein expressed by the bacteria when present in a tick.

Clinical Trials 76

Clinical Trials Clinical Trials Vaccination Vaccine 76

Roots Analysis

AUGUST 31, 2023

coli bacteria, as well as lambda bacteriophage, can adapt to the alterations in the composition of their nutrient medium. Further, the expression of any gene is dependent on the rate at which it is transcribed into mRNA and translated into proteins. When activator binds to the operon, it either speeds up or permits gene expression.

Gene 40

Gene Gene Therapy Gene Expression Regulation 40

XTalks

JUNE 2, 2023

Nitrates and nitrites serve several purposes in food preservation since they inhibit the growth of harmful bacteria, help to maintain the pink or red color of cured meats and contribute to the distinctive flavor of cured meats. However, there are concerns about the consumption of nitrates and nitrites.

Production 52

Production Bacteria Marketing Containment 52

The Pharma Data

JULY 21, 2021

This investigational multivalent protein subunit vaccine uses an established mechanism of action for a Lyme disease vaccine that targets the outer surface protein A (OspA) of Borrelia burgdorferi , the bacteria that cause Lyme disease. About Lyme Disease. According to the U.S.

Vaccination 52

Vaccination Vaccine Trials Bacteria 52

XTalks

APRIL 17, 2023

It was caused by contaminated ice cream products manufactured by Blue Bell Creameries, a popular ice cream company based in Texas. The outbreak was caused by the bacterium Listeria monocytogenes , which was found in several samples of Blue Bell ice cream products, as well as in the company’s manufacturing facilities.

Contamination 98

Contamination Bacterium Production Regulation 98

The Pharma Data

OCTOBER 14, 2020

The AOP Orphan Group manufactures 80% of its drugs in Europe and has more than 20 subsidiaries and representative offices across the whole of Europe as well as in the United Arab Emirates and Israel. The funds will be used to bring Ori’s innovative manufacturing platform to the market. million if certain project milestones are met.

Clinical Trials 52

Clinical Trials Clinical Trials Manufacturing Trials 52

XTalks

AUGUST 2, 2023

Most of the company’s revenue comes from the manufacture and sale of biopharmaceutical products. Johnson & Johnson’s Top 5 Best-Selling Drugs of 2022: 1) Stelara (ustekinumab) Stelara is an immunosuppressant biologic therapy that blocks the IL-12 and IL-23 proteins that play a role in plaque psoriasis and Crohn’s disease.

Sales 98

Sales Manufacturing FDA Approval Life Science 98

Pharmaceutical Technology

MARCH 24, 2023

TB is caused by the bacillus Mycobacterium tuberculosis and is transmitted when infected individuals expel bacteria into the air (e.g., Fox says adjuvant protein subunit vaccines can be a safer approach compared to live attenuated virus vaccines as there is a minimized risk of developing side effects. by coughing).

Vaccination 162

Vaccination Vaccine Clinical Trials Clinical Trials 162

The Pharma Data

MAY 14, 2021

Charles River loses a battle over harvesting horseshoe crabs used for testing bacteria in drugs ( STAT ). Vaccine maker Northwest Bio claims it’s in the homestretch for its manufacturing expansion in the UK ( Endpoints ). In Focus: International. Coronavirus Pandemic.

Gene Therapy 52

Gene Therapy Gene Vaccination Vaccine 52

XTalks

DECEMBER 24, 2020

Distilleries and breweries used their production facilities to make hand sanitizers while car manufacturers such as GM, Ford and Tesla, and vacuum maker Dyson , pledged to convert their assembly lines to make ventilators. Most antibody drugs and vaccines have been developed to target parts of the spike protein.

Life Science 111

Life Science Vaccination Vaccine Gene 111

The Pharma Data

OCTOBER 26, 2020

AR-711 exhibits high affinity for SARS-CoV-2 spike protein, approximately 10-fold or higher than mAb candidates currently in late stage clinical testing. AR-701 is a cocktail of fully human mAbs discovered from convalescent COVID-19 patients that are directed at multiple envelope proteins of the SARS-CoV-2 virus. AR-701 (COVID-19).

Antibody 52

Antibody Genetic Engineering Development Clinical Trials 52

Drug Discovery World

DECEMBER 14, 2023

The Institute has particular strengths in understanding how cancer hijacks the cell’s energy factories and how it manipulates the body to provide the resources it needs to grow and spread, like protein scaffolding and blood vessels. Discoveries in these areas will identify new treatments which will become the cancer drugs of the future.”

Drugs 75

Drugs Life Science Research Scientist 75

XTalks

DECEMBER 17, 2021

As Moderna’s first ever commercial product, the company wasn’t positioned for large-scale manufacturing of its COVID-19 Spikevax vaccine. Initial lab studies, including one from South Africa, show that vaccine-induced antibodies may be less effective at neutralizing Omicron.

Life Science 98

Life Science Vaccination Vaccine Trials 98

XTalks

DECEMBER 22, 2021

RNA, and its protein-generating form messenger RNA (mRNA) discovered in 1961 , has quickly transitioned from being an obscure, finicky molecule that is difficult to work with, to becoming a significant cornerstone of therapeutic innovation in pharma and biotech. The RNA Revolution: From mRNA Vaccines to RNA Editing.

Life Science 98

Life Science RNA Vaccination Vaccine 98

XTalks

APRIL 12, 2021

synuclein is a hallmark of Parkinson’s, and it’s been postulated that dysfunction of GCase in neurons could contribute to build-up of the protein and the resulting inflammation and neurodegeneration characteristic of the disorder. Research suggests that some gut bacteria can increase levels of ?-synuclein Cellular accumulation of ?-synuclein

Gene Therapy 96

Gene Therapy Gene Trials Development 96

The Pharma Data

OCTOBER 19, 2020

There are more than 90 different types of pneumococcal bacteria which can affect adults differently than children. The global prevalence of pneumococcal disease, an infection caused by bacteria called Streptococcus pneumoniae , is evolving. Plans for global regulatory licensure applications, beginning with the U.S.

Vaccination 52

Vaccination Vaccine Immune Response Containment 52

The Pharma Data

JUNE 18, 2021

PREVNAR 20 includes capsular polysaccharide conjugates for the 13 serotypes (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F) already included in Prevnar 13 ® (Pneumococcal 13-valent Conjugate Vaccine [Diphtheria CRM 197 Protein]). Global President of Pfizer Vaccines. “We

Vaccination 52

Vaccination Vaccine FDA Approval Containment 52