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The evolution of assays for immuno-oncology research

Drug Discovery World

The first such research dates back to 1891, when William Coley attempted to inject heat-inactivated bacteria to treat osteosarcoma. Cancer is a complex heterogenous multistep disease characterised by uncontrolled cell proliferation combined with a dysregulated immune response. This continues to be the standard of care.

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Gene Switch: A Novel Platform for Switching Genes On and Off

Roots Analysis

coli bacteria, as well as lambda bacteriophage, can adapt to the alterations in the composition of their nutrient medium. An additional level of genetic control is provided by gene switches that are located upstream of the promoter region. These genetic switches assist transcription factors in binding to the promoter region.

Gene 40