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Guide to using AAV vectors in gene therapy

Drug Discovery World

The event aimed to help the audience understand the AAV workflow, from upstream methods for AAV production and validation to downstream analysis of the packaged product for enhanced therapeutic development. For the AAV packaging service, what is the titer of the viral particles? Why are those important? How is the titer determined?

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Guide to using AAV vectors in gene therapy

Drug Discovery World

The event aimed to help the audience understand the AAV workflow, from upstream methods for AAV production and validation to downstream analysis of the packaged product for enhanced therapeutic development. For the AAV packaging service, what is the titer of the viral particles? Why are those important? How is the titer determined?

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Women in Science Who Have Paved the Way Forward in Genetics

XTalks

The Human Genome Project recently marked 20 years since the publication of the first full sets of human genomic sequences, an endeavor that spanned well over a decade. Today, new next-generation sequencing technologies allow for the sequencing of complex genomes within just a day or two.

Genetics 119
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The doors CRISPR libraries have and will open in phenotypic drug screening 

Drug Discovery World

In an effort to defend themselves against viral infection, bacterial cells capture and copy DNA fragments of bacteriophages into their genome. In the event of an attack from similar bacteriophages, the bacteria can recognise these segments and use this to discern and cleave the viral DNA, which disrupts the viral gene function.

Genome 52
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CRISPR breakthroughs: New solutions for common diseases

Drug Discovery World

Rolf Turk , Senior Manager, Genomics Medicine at Integrated DNA Technologies, examines how CRISPR is being used to enhance cancer therapies. Herpesviridae, Polyomaviridae, and Papillomaviridae), bacteria (e.g., CRISPR diagnostics have successfully detected various pathogens, including RNA viruses (eg.

DNA 98