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Gum disease may lie at the root of some arthritis flareups

Medical Xpress

But new research may help explain this link between gum disease and an otherwise disparate condition. It's a well-documented medical mystery: Patients with gum disease are less likely to respond to rheumatoid arthritis treatments.

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Commensal bacteria ‘vaccine’ may safely prep immune cells for meningitis-causing cousin

Scienmag

Researchers have produced vaccine-like immune responses to a dangerous bacterium by colonizing 26 healthy volunteers with a related, but harmless, commensal bacterial species.

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Research Shows How Gut Bacteria Can Help Fight Cancer

XTalks

Increasing research into the gut microbiome has revealed new and emerging roles for the ‘good bacteria’ in our bodies, with the latest being a new study that shows how they can help the immune system attack cancer cells. Related: Characterizing the Tumor Microbiome: Bacteria Found in Tumors May Predict Response to Therapy.

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Infant antibiotic exposure can affect future immune responses toward allergies

Scienmag

Early life exposure to antibotics in utero and through mother’s milk disrupts beneficial gut bacteria, compromising T-cell development, Rutgers research shows Exposure to antibiotics in utero and infancy can lead to an irreversible loss of regulatory T-cells in the colon-a valuable component of the immune system’s response toward allergens (..)

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Harnessing the microbiome: The new frontier in drug discovery and testing 

Drug Discovery World

Paul Denslow , CEO, Intus Bio, discusses how a new approach to tracking gut bacteria can revolutionse our understanding of the microbiome and bring about new discoveries for therapeutics. It’s a long-held doctrine that there’s no effective method to track the microbiome during drug research and development.

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Study insights may aid TB vaccine development

Drug Discovery World

New research has furthered our understanding of the immune-related factors that drive infection and disease, which will be necessary for an effective tuberculosis (TB) vaccine to be developed. infection in infants who became infected with the bacteria but did not progress to active TB. Most individuals infected with M.tb

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US researchers decipher how one gut bacterium influences immunity

Drug Discovery World

But with hundreds of bacterial species populating our gastrointestinal tract, it’s a daunting task to pinpoint which molecules made by which bacteria affect which biological processes—and how they do so. Such knowledge is essential for learning how to manipulate gut bacteria to treat or prevent illness. muciniphila’s cell membrane.