pharmaphorum

AUGUST 5, 2021

Understanding the mechanism of PPIs and developing methods to target aberrant ones has been a key strategy in drug development. In comparison with the classic, small molecule drug discovery approach, the modulation of PPIs is more challenging. The interface is highly hydrophobic, hence any compounds containing water would be repelled.

Protein 126

Protein Gene Bioassay DNA 126

Drug Discovery World

AUGUST 12, 2022

This has an important knock-on effect if the compound’s MF and MW are calculated algorithmically from the structure diagram, as they may no longer accurately reflect the effective MF value which has been normalised to the version of the salt/hydrate that contains a single molecule of the parent compound. Suppose you want to makeup a 0.1

Drugs 52

Drugs Bioassay Development Research 52

Drug Discovery World

MAY 4, 2023

Professor Sonika Bhatnagar explores how artificial intelligence is enabling drug discovery at rates never seen before. Here started the story of drug discovery. The magic bullet was the drug, while the specific mark it would reach in the syphilis causing bacteria to eliminate the disease was the drug target.

Medicine 52

Medicine Protein Drugs Bioassay 52

Drug Discovery World

NOVEMBER 30, 2023

This conditional activation is intended to focus immune attack more specifically against tumour cells and minimise damage to healthy cells, a major challenge for current oncology drugs and development efforts. The post Reflecting on PEGS Europe 2023 appeared first on Drug Discovery World (DDW).

Antibody 59

Antibody Protein Engineer In-Vivo 59

The Pharma Data

MAY 13, 2021

Fructose Containing Sugars at Normal Levels of Consumption Do Not Effect Adversely Components of the Metabolic Syndrome and Risk Factors for Cardiovascular Disease. Nat Rev Drug Discov. The obesity epidemic and food addiction: clinical similarities to drug dependence. J Psychoactive Drugs. Curr Drug Abuse Rev.

Insulin 52

Insulin Production Hormones Medicine 52