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Evaluating methods targeting Protein-Protein Interactions

pharmaphorum

Protein-protein interactions (PPIs) are becoming increasingly relevant in the pathology of many diseases, including cancer. PPIs are an integral part of the physiology of living organisms, as complexes which control biological pathways mediated by proteins. These regions are critical for optimal interactions between proteins.

Protein 126
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Reimagining cell engineering with picodroplet microfluidic technology

Drug Discovery World

Cell engineering is bringing life science into a new era of biotherapeutic discovery and development, disease modelling, and synthetic biology research. Within picodroplets, single cells are assayed to identify specific proteins to find rare cells of interest or cells with high productivity.

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Can artificial intelligence help craft new medicines?

Drug Discovery World

The drug target for Penicillin is a protein that helps bacteria to synthesise its cell wall. One of the first and most basic requirements for a protein to be characterised as a drug target is to show that inhibiting its function prevents the disease. Salvarsan was soon overtaken by the Penicillin antibiotics.