pharmaphorum

JANUARY 18, 2023

The DNA of these so-called ‘genetic superheroes’ may contain clues about how to treat severe disease. In our experience of running 20+ precision medicine studies, there are a few design principles that every research programme – from biobanks to clinical trials – should consider. Giving participants something in return.

Genetic Disease 77

Genetic Disease Genetics Research Genome 77

XTalks

FEBRUARY 4, 2021

Biobanks are used for the coordination of high-yield patient sample collection. Moreover, biobanks are no longer passive biorepositories for accrual of samples and serve a more utilitarian function in identifying and coordinating specific research cohorts for longitudinal and prospective studies. Biobanking Models.

Research 98

Research Biobanking Drugs Genome 98

XTalks

APRIL 15, 2021

For example, the sequence environment around the ADRA2B gene contains many other nearby genes, so a simple approach to SNP selection would generate spurious results. Though the HERMES, and the related 2010 CHARGE study, performed large heart failure genomic association analysis, both consortia relied on genotyping and self-reported data.

Development 98

Development Drugs Genome Genomics 98