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Supercharging AI-drug discovery with strategic multiomic biobanks 

Drug Discovery World

Narain , PhD, President and CEO of BPGbio asks how a better calibre of biobanks in life sciences can lead to more drugs making it to market. Not all biobanks are created equal Biobanks provide a treasure trove of clinical data for exploration with AI tools. But the utility of biobanks varies.

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Why early participant engagement is now a top priority in genetic disease research

pharmaphorum

Pharmaceutical companies and biotechs are also adapting their approaches, launching patient finding and engagement programmes that can start years before clinical trials begin and allow them to run ‘recontact by genotype’ studies that the Resilience Project would have liked to do. Giving participants something in return.

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Estonia National Biobank to sequence 10,000 whole genomes 

Drug Discovery World

To date, the samples for the Biobank have been genotyped using microarray-based methods. The post Estonia National Biobank to sequence 10,000 whole genomes appeared first on Drug Discovery World (DDW).

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Study reveals first genetic links in ME and Chronic Fatigue Syndrome

Drug Discovery World

Each circle represents a disease-associated SNP genotype, edges represent their co-association in patients in disease signature(s), and colours represent distinct patient sub-populations. Using the PrecisionLife platform the study identified 14 novel genetic associations with ME/CFS from the UK Biobank cohort. Copyright: PrecisionLife.

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Can genetic data be a magic bullet for drug R&D?

pharmaphorum

As part of the US government’s Cancer Moonshot initiative, a Cancer Moonshot Biobank was launched that asked participants to donate biospecimens and associated health information to aid research. The focus of research projects on gathering data, particularly genetic data, is now common place in nationwide health-focused initiatives.

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The biotech improving immunotherapies with AI

Drug Discovery World

Where cancers were previously understood by their tissue of origin and cell morphology, we can now define them based on their genotypes and molecular drivers. Reece A: Does immunotherapy represent the future of cancer care?

Genome 52
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Biorepositories as a Guiding Resource for Research & Drug Discovery

XTalks

Biobanks are used for the coordination of high-yield patient sample collection. Moreover, biobanks are no longer passive biorepositories for accrual of samples and serve a more utilitarian function in identifying and coordinating specific research cohorts for longitudinal and prospective studies. Biobanking Models.