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Turning science into business: Exploiting macrophage biology

Drug Discovery World

LC : As we describe in Nature Reviews Cancer (NRC), scientists have known since the 1970s that tumours were populated by immune cells; however, it took several years of pre-clinical studies to prove that macrophages were key players in tumour progression. DS: Congratulations on the publication of your discoveries in Nature Reviews Cancer.

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What to expect from PEGS Europe 2023: Day 2

Drug Discovery World

Gail Calvert, Field Application Scientist, Sartorius UK, on: ‘Leveraging integrated and advanced technologies for successful cell line development’. Ahead of protein and antibody engineering conference PEGS Europe 2024 in Lisbon, DDW’s Megan Thomas looks at what to expect from each track of the annual biologics technology meeting.

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What to expect from PEGS Europe 2023: Day 3

Drug Discovery World

Novel/alternative ML-enabled screening technologies for higher POS Following chairperson’s remarks from M Frank Erasmus, PhD, Head, Bioinformatics, Specifica, there will be four presentations and a panel discussion. Ali Madani, PhD, Founder and CEO, Profluent Bio, on: ‘Protein engineering with large language models’.

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What to expect from PEGS Europe 2023: Day 1

Drug Discovery World

Sebastian Jaeger, PhD, Senior Scientist, ADCs & Targeted NBE Therapeutics, Merck Healthcare KGaA, on: ‘Evaluation of Fcab-drug conjugates as a novel antibody-based format for targeted drug delivery’.

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FAIR Game: making data work harder in the race to market 

Drug Discovery World

For pharma and biotech companies – whether working on small or large molecule drugs, or cell and gene therapies – this means empowering scientists with better and faster data management approaches, best practices, and leading technologies so they can pinpoint new molecules and formulations and modify existing ones more easily and quickly.

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Reflecting on PEGS Europe 2023 

Drug Discovery World

DDW’s Megan Thomas attended PEGS Europe 2023 in Lisbon, Portugal, from Tuesday 14 November to Thursday 16 November 2023. The company’s goal is to accelerate functional characterisation and shortenoptimisation time in antibody discovery and t-cell workflows. GSK has developed high-throughput mammalian and E.

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Synthetic biology tools advancing and accelerating drug discovery efforts

Drug Discovery World

Even as methods in DNA synthesis continue to advance, scientists’ reliance on third-party companies for synthesising DNA creates a bottleneck, impeding research timelines. . “If Anita Ramanathan outlines four synthetic biology approaches that are improving and accelerating drug discovery. .

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