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International team identifies a new regulatory pathway in bladder cancer

Scienmag

GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma Credit: Insilico Medicine August 20th, 2020, Hong Kong – Researchers from Johns Hopkins University in collaboration with Insilico Medicine announce the publication of a new research paper titled “GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma” (..)

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Can technology help diversify clinical trials?

pharmaphorum

This is the second in a two-part series examining how pharma can embrace the DEI agenda to create more effective medicines through more representative clinical trials. data processing systems that support bioinformatics modelling) and digital record systems (e.g. You can read part one of this article here. About the interviewees.

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Ferrets, cats and civets most susceptible to coronavirus infection after humans

Scienmag

Ducks, rats, mice, pigs and chickens had lower or no susceptibility to infection Credit: Javier Delgado Humans, followed by ferrets and to a lesser extent cats, civets and dogs are the most susceptible animals to SARS-CoV-2 infection, according to an analysis of ten different species carried out by researchers at the Centre for Genomic Regulation […]. (..)

Genome 52
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Who are the AACR Scientific Achievement Award winners?

Drug Discovery World

Carl H June, MD, FAACR – Lifetime Achievement in Cancer Research June, a Fellow of the AACR Academy, is the Richard W Vague Professor in Immunotherapy, Director of the Center for Cellular Immunotherapies, and Director of the Parker Institute for Cancer Immunotherapy in the Perelman School of Medicine at the University of Pennsylvania.

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Global impact: How regulatory affairs is shaping development of cutting-edge pharma innovation

pharmaphorum

Collaboration when innovating in areas of high unmet medical need is critical and at Astellas, it means experts with highly specialised knowledge of these new discoveries often work in close partnership with regulators. “We In principle, this goes beyond medicines. It’s through this collaboration that we help shape the future.”.

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STAT+: Foundation charges cancer patients $83,000 for unproven but promising experimental drug

STAT News

It works with commercial partners and researchers at the Washington University School of Medicine in St. Therapeutic vaccines represent the next frontier in cancer medicine. Although the FDA  allows drugmakers to charge patients  for unproven medicines provided for compassionate use, it’s uncommon and controversial.

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Big data – charting a new path to drug discovery and development

Drug Discovery World

It is also anticipated that the Food and Drug Administration (FDA) and European Medicines Agency (EMA) will provide more guidance on requirements for AI/ML-enabled processes across the pharmaceutical industry as they become more mainstream.