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The Silent Mutations That Gave Coronavirus a Selective Advantage

XTalks

The answer may lie in the genetic code of the virus, which scientists at Duke University have found contains several silent mutations that affect protein folding. The researchers focused on the spike proteins that protrude from the surface of the coronavirus, which are responsible for viral attachment and entry into host cells.

RNA 98
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Wainua (Eplontersen) Now FDA-Approved for Rare Disease ATTRv-PN

XTalks

In individuals affected by ATTR, which includes both hereditary and wild-type (non-hereditary) variants, the TTR protein forms fibrils that accumulate in various tissues. These tissues comprise peripheral nerves, the heart, gastrointestinal system, eyes, kidneys, central nervous system, thyroid and bone marrow.

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Thermo Fisher, Qiagen and Others Assure Their COVID-19 PCR Tests Detect Omicron

XTalks

While researchers are still working out the epidemiological, clinical and molecular details of Omicron, so far, it is known that the variant is laden with up to 50 mutations, 30 or so of which are just in its outer spike (S) protein. This early identification is very important in helping us track and understand the spread of the B.1.1.529

Gene 105
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Izervay Becomes Second FDA-Approved Drug for Geographic Atrophy

XTalks

Izervay contains avacincaptad pegol sodium, an effective complement C5 inhibitor. Avacincaptad pegol combines an RNA aptamer with a roughly 43-kiloDalton (kDa) branched polyethylene glycol (PEG) molecule. How Does Izervay Work?

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Lab to jab in 100 days: manufacturing flexibility for future rapid responses

Pharmaceutical Technology

According to CEPI: “Achieving the 100 Days Mission would give the world a fighting chance of containing a future outbreak before it spreads to become a global pandemic.”. The mission was first put forward during the UK’s G7 Presidency of June 2021, with support from representatives of the life sciences industry.

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The Utility of Liquid Biopsy in Oncology Clinical Trials

XTalks

Exosomes are extracellular vesicles that contain molecular cargoes (such as various proteins, RNAs and DNAs) specific to the origin cell. Also, exosomes are mostly being used for the detection of circulating RNA and microRNA. “An Exosome-Based Liquid Biopsy in Oncology.

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CureVac : CureVac and Bayer Join Forces on COVID-19 Vaccine Candidate CVnCoV

The Pharma Data

About Bayer Bayer is a global enterprise with core competencies in the life science fields of health care and nutrition. Bayer Forward-Looking Statements This release may contain forward-looking statements based on current assumptions and forecasts made by Bayer management. ak (2021-0003E).