Rethinking Clinical Trials

JULY 11, 2023

The NIH Collaboratory is excited to announce the addition of LE8 Bot + BackUp (or Using Artificially Intelligent Text Messaging Technology to Improve American Heart Association's Life's Essential 8 Health Behaviors) to its portfolio of innovative Demonstration Projects.

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Rethinking Clinical Trials

JUNE 6, 2023

The INSPIRE Demonstration Project is supported within the NIH Pragmatic Trials Collaboratory by a grant from the National Institute of Allergy and Infectious Diseases (NIAID). All of the materials from the 2023 Steering Committee meeting are now available.

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Rethinking Clinical Trials

JULY 19, 2022

At the NIH Pragmatic Trials Collaboratory’s annual Steering Committee this spring, we sat down with investigators from the PRISM Demonstration Projects to discuss their progress in the first year of study implementation. All 3 studies began enrollment last year. Natalia Morone of Boston University and Boston Medical Center.

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Rethinking Clinical Trials

SEPTEMBER 13, 2022

The deadline to submit letters of intent for the NIA IMPACT Collaboratory’s Demonstration Projects Program has been extended to September 30, 2022. This summer, the IMPACT Collaboratory announced a request for applications for its Demonstration Projects Program.

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Rethinking Clinical Trials

JULY 26, 2022

At this year’s annual meeting of the NIH Pragmatic Trials Collaboratory Steering Committee, we interviewed investigators from 3 Demonstration Projects in different phases of the trial life cycle. Learn more about these innovative Demonstration Projects in the brief video updates below. The project is led by Drs.

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Rethinking Clinical Trials

JULY 12, 2022

The NIA IMPACT Collaboratory will publish new funding opportunities on August 15 for a pilot grants program and a demonstration projects program. The post July 12, 2022: IMPACT Collaboratory to Publish Funding Opportunities for Pilot and Demonstration Project Programs appeared first on Rethinking Clinical Trials.

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Rethinking Clinical Trials

JULY 19, 2023

From left: Dr. Christine Goertz and Dr. Adam Goode of the IMPACt-LBP Demonstration Project In this Friday’s PCT Grand Rounds, Dr. Christine Goertz and Dr. Adam Goode of Duke University will present “Implementing New Care Pathways for Low Back Pain in Academic Healthcare Systems: Early Lessons From IMPACt-LBP.”

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Rethinking Clinical Trials

JUNE 21, 2023

ICD-Pieces , an NIH Collaboratory Demonstration Project, used a novel information technology platform to identify patients with concurrent chronic kidney disease, diabetes, and hypertension and deliver evidence-based interventions to improve patient outcomes.

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Rethinking Clinical Trials

DECEMBER 18, 2023

Both projects are in their planning phase. The project will leverage the existing electronic health record and patient portal, PREPARE for Your Care materials to assist patients with completion of advance care planning, virtual healthcare navigators, and electronic nudges. Learn more about I CAN DO Surgical ACP.

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Rethinking Clinical Trials

JULY 3, 2023

In a new article published online ahead of print in JAMIA , the NIH Pragmatic Trials Collaboratory’s Demonstration Project teams reflect on the health equity challenges encountered by their trials and share the specific strategies they used to mitigate sources of potential bias and increase the generalizability of research results.

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Rethinking Clinical Trials

AUGUST 16, 2022

Patrick Heagerty to reflect on the role of the Biostatistics and Study Design Core Working Group in helping the Demonstration Project teams design trial and analyze the data, and to discuss their focus for the Core’s future contributions to pragmatic clinical trials.

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Rethinking Clinical Trials

OCTOBER 10, 2023

Ethics and regulatory onboarding documentation for the NIH Pragmatic Trials Collaboratory’s newest Demonstration Projects are now available. All of the projects are in their 1-year planning phase. Ethics and regulatory documentation for all of the Demonstration Projects is available on our Data and Resource Sharing page.

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Rethinking Clinical Trials

JULY 7, 2022

Emily O’Brien to reflect on the role of the Patient-Centered Outcomes Core in helping the Demonstration Project teams plan and implement their trials, and to discuss their focus for the Core’s future contributions to pragmatic clinical trials. What strategies have Demonstration Projects used to overcome these barriers?

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Rethinking Clinical Trials

JULY 31, 2023

Pilot and Feasibility Testing: The LIRE Example Description NIH Collaboratory investigator Dr. Jerry Jarvik, principal investigator of the LIRE Demonstration Project, discusses pilot and feasibility testing in pragmatic clinical trials.

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Rethinking Clinical Trials

DECEMBER 18, 2023

This training workshop introduces concepts in the design, conduct, and implementation of embedded pragmatic clinical trials (ePCTs), and provides firsthand ePCT experiences and case studies from the NIH Pragmatic Trials Collaboratory Demonstration Projects.

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Rethinking Clinical Trials

JUNE 29, 2022

Pragmatic clinical trials experienced significant impacts of COVID-19 on trial activities, according to a survey of NIH Pragmatic Trials Collaboratory Demonstration Projects published last month in Trials. All of the Demonstration Projects were able to adapt to pandemic-related changes.

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Rethinking Clinical Trials

JULY 17, 2023

Ibemere will work closely with the Implementation Science Core and the GRACE Demonstration Project team during her fellowship year. Dr. McLeod will work closely with the Health Equity Core and the Nudge Demonstration Project team during her fellowship year.

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Rethinking Clinical Trials

AUGUST 1, 2023

Vince Mor discuss what it means to design a pragmatic trial with implementation in mind, and they share examples from 2 of the Collaboratory’s Demonstration Projects—ABATE Infection and PROVEN.

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Rethinking Clinical Trials

JUNE 14, 2023

BeatPain Utah , an NIH Collaboratory Demonstration Project, is studying real-world implementation of a telehealth physical therapy strategy for patients with chronic back pain in primary care clinics of federally qualified health centers. ” The Grand Rounds session will be held on Friday, June 16, 2023, at 1:00 pm eastern.

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Rethinking Clinical Trials

JULY 5, 2023

This training workshop introduces concepts in the design, conduct, and implementation of embedded pragmatic clinical trials (ePCTs) and provides firsthand ePCT experiences and case studies from the NIH Pragmatic Trials Collaboratory Demonstration Projects.

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Rethinking Clinical Trials

AUGUST 4, 2023

Biography Gregory Simon, MD, MPH Senior Investigator, Kaiser Permanente Washington Health Research Institute SPOT Demonstration Project PI Health Care Systems Interactions Core Chair Related View more content from the Disseminating, Implementing, and Sustaining Evidence-Based Practices into Clinical Care: NIH-Hosted Workshop.

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Rethinking Clinical Trials

MARCH 1, 2023

” Kuklinski and Sterling are the principal investigators of GGC4H , an NIH Pragmatic Trials Collaboratory Demonstration Project. Stacy Sterling will present “Adoption, Implementation and Sustainment of Family-Focused Prevention in Health Care Systems: How Do We Get There?”

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Rethinking Clinical Trials

MARCH 15, 2023

IMPACt-LBP, an NIH Pragmatic Trials Collaboratory Demonstration Project, enrolled its first study participant this week. Congratulations to the IMPACt-LBP study team for reaching this important project milestone!

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Rethinking Clinical Trials

AUGUST 9, 2023

appeared first on Rethinking Clinical Trials.

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Rethinking Clinical Trials

FEBRUARY 23, 2023

This training workshop introduces concepts in the design, conduct, and implementation of embedded pragmatic clinical trials (ePCTs) and provides firsthand ePCT experiences and case studies from the NIH Pragmatic Trials Collaboratory Demonstration Projects.

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Rethinking Clinical Trials

JANUARY 8, 2024

Learn more about the NIH Collaboratory Demonstration Projects. This work was a collaboration between the Electronic Health Records Core and the Patient-Centered Outcomes Core of the NIH Pragmatic Trials Collaboratory.

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Rethinking Clinical Trials

DECEMBER 20, 2022

This training workshop introduces concepts in the design, conduct, and implementation of embedded pragmatic clinical trials (ePCTs), and provides firsthand ePCT experiences and case studies from the NIH Pragmatic Trials Collaboratory Demonstration Projects. Speaker Biographies. Program Overview. Participant Guide. Agenda & Slides.

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Rethinking Clinical Trials

AUGUST 8, 2023

Biography Gregory Simon, MD, MPH Senior Investigator, Kaiser Permanente Washington Health Research Institiute SPOT Demonstration Project PI Health Care Systems Interactions Core Chair Coordinating Center Leadership The post Pilot-Testing Interventions in Pragmatic Trials: SPOT Case Study appeared first on Rethinking Clinical Trials.

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Pharma Mirror

MARCH 31, 2022

million collaborative UKRI-funded project as part of the medicines manufacturing challenge. The post Symbiosis announces successful completion of UK Research and Innovation (UKRI) project, which will enhance the manufacturing supply chain for ATMPs within the UK appeared first on Pharma Mirror Magazine.

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Rethinking Clinical Trials

JULY 20, 2023

BeatPain Utah , an NIH Collaboratory Demonstration Project, is studying real-world implementation of a telehealth physical therapy strategy for patients with chronic back pain in primary care clinics of federally qualified health centers. Guilherme Del Fiol presented on their experiences during the June 16 session of Grand Rounds.

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Pharmaceutical Technology

NOVEMBER 1, 2022

Our programme is designed to highlight excellence within the sector by looking at a range of corporate activities including deals, business projects and company initiatives, both internal and in the community. What is Social? Is your company ranked? Ranking Categories.

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Rethinking Clinical Trials

JANUARY 24, 2023

Shruti Gohil The INSPIRE Demonstration Project went live this month, with a new order entry screen being activated in the electronic health record at 51 hospital sites randomized to the intervention.

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Rethinking Clinical Trials

JUNE 14, 2023

Updated study snapshots and ethics and regulatory documentation are now available for the IMPACt-LBP and INSPIRE trials, both NIH Pragmatic Trials Collaboratory Demonstration Projects. The project is supported within the NIH Collaboratory under an award from the National Institute of Allergy and Infectious Diseases.

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Rethinking Clinical Trials

JANUARY 30, 2023

The membership of both Cores draws from across the program to support the design and implementation of the NIH Collaboratory Demonstration Projects. “By The Health Equity Core provides leadership and guidance to help the Demonstration Projects and investigators be more equitable in research.

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Rethinking Clinical Trials

AUGUST 22, 2022

The NIH Pragmatic Trials Collaboratory is pleased to announce that the IMPACt-LBP Demonstration Project received approval this month to transition from the planning phase to the implementation phase. The project is led by Drs. Learn more about IMPACt-LBP.

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Rethinking Clinical Trials

MAY 8, 2023

Attendees will participate in facilitated, hands-on learning activities and interact with principal investigators of pragmatic clinical trials embedded in healthcare systems, including NIH Collaboratory Demonstration Projects.

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Medical Xpress

APRIL 25, 2023

The complete findings of the RCT-DUPLICATE demonstration project are published today in JAMA.

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