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Why genomic healthcare data matters in the development of new therapies 

Drug Discovery World

Genomic healthcare data is critical to identify disease risk, ancestry, traits and response to medicines and aids in the development of new targeted therapies – precision medicines. DDW’s Megan Thomas observes developments of accessibility in this sector and the potential impact. . The origins . References .

Genome 98
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Personalising whole genome sequencing doubles diagnosis of rare diseases 

Drug Discovery World

In 2018, the UK’s department of health announced an NHS Genomic Medicine Service, which allows patients with rare diseases to have their entire genetic code read in the hope of providing a much-needed diagnosis. It also detected potential disease-causing variants in a further 3.9% The study . of patients. .

Genome 52
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CRISPR therapies targeting the next breakthrough in oncology

pharmaphorum

The potential of CRISPR technology has been a hot topic in the industry ever since it was first developed, but as trials progress further into the clinic, what therapeutic areas could be set to benefit? Cancer is a genetic disease, caused by certain changes in the way that genes control cell function, such as how they grow and divide.

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Searching for answers in rare epilepsy

pharmaphorum

She developed fine for the first six months of her life,” he says, “but then she stopped smiling, she stopped giggling, and stopped taking an interest in her surroundings. Everything the 100,000 Genomes Project does has to be rubber-stamped by the patients”. She had a glazed look in her eyes, almost like she was blind.

Genome 86
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Searching for answers in rare epilepsy

pharmaphorum

She developed fine for the first six months of her life,” he says, “but then she stopped smiling, she stopped giggling, and stopped taking an interest in her surroundings. Everything the 100,000 Genomes Project does has to be rubber-stamped by the patients”. She had a glazed look in her eyes, almost like she was blind.

Genome 73
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The era of precision neuroscience

Drug Discovery World

The prevalence of these diseases has grown substantially in recent decades due to an increasing global population, longer life expectancies and increasing morbidity with predisposing risk factors. This now represents one of the most challenging and costly burdens to health and social care systems and societies worldwide.

Genome 64