pharmaphorum

JANUARY 24, 2023

Drug development has long been an issue for the pharma industry, due to the expense and the high failure rate of potential treatments. Ben Hargreaves finds that the vast amount of genetic data that exists today could help provide a faster, more targeted way of developing new drug candidates.

Genetics 92

Genetics Drugs Genome Project Biobanking 92

Drug Discovery World

MARCH 13, 2024

Thanks to significant investment by the government into research and development, Singapore has become a leading centre for biomedical sciences in Asia. Following this, a medical innovation and development centre, Biopolis Hub, was opened in 2005. UK-based molecular diagnostics group Yourgene operates in Singapore.

Life Science 69

Life Science Genome Genomics Research 69

The Pharma Data

MARCH 1, 2022

to build a scalable data, analytics, and infrastructure platform This collaboration aims at capturing translational disease insights from large external healthcare biobanks and maximizing value of data for drug discovery and precision medicine. Boehringer Ingelheim partners with Lifebit Biotech, Ltd. More information at www.lifebit.ai.

Biobanking 52

Biobanking Genome Genomics Genome Project 52

pharmaphorum

SEPTEMBER 13, 2022

Although early accounts of an illness akin to leukaemia can be traced back to Ancient Greece, the first official description of blood cancer didn’t appear until 1832, when British pathologist and pioneer of preventative medicine Thomas Hodgkin used the controversial concept of micrology to identify the abnormalities in the lymphatic system.

Genome Project 94

Genome Project Genome Genomics DNA 94

pharmaphorum

FEBRUARY 25, 2021

The detail remains to be written,” he said, explaining that all four nations would now develop their own action plans for the implementation of the framework. “We The Scottish Government has supported the transition of genomic testing for inherited rare disease from the research setting into routine care,” she went on. “As

Genome 93

Genome Genomics Genetics Medicine 93

pharmaphorum

SEPTEMBER 9, 2020

Geneticist Dr Charles Steward has spent his career studying the human genome – but his work became much more personal when his children were diagnosed with severe neurological diseases. Everything the 100,000 Genomes Project does has to be rubber-stamped by the patients”. For some people, a job is more than just a job.

Genome 86

Genome Genomics Genetics Genome Project 86

Roots Analysis

AUGUST 31, 2023

Recent advances in DNA sequencing technologies have led to significant developments in healthcare-focused research on precision medicine and diagnostics. Nutrigenomics is the science studying the relationship between human genome, nutrition and health.

Genome 40

Genome Genomics Genetics Gene 40

pharmaphorum

MARCH 25, 2021

The COSMIC (Catalogue of Somatic Mutations in Cancer) database, operated by the Wellcome Sanger Institute, grew out of the work of the Cancer Genome Project and has been gathering data on mutations associated with specific cancers for almost 17 years. The post COSMIC database matches drugs to cancer mutations appeared first on.

Drugs 59

Drugs Genome Project Genome Genomics 59

pharmaphorum

SEPTEMBER 9, 2020

Geneticist Dr Charles Steward has spent his career studying the human genome – but his work became much more personal when his children were diagnosed with severe neurological diseases. Everything the 100,000 Genomes Project does has to be rubber-stamped by the patients”. For some people, a job is more than just a job.

Genome 73

Genome Genomics Genetics Genome Project 73

The Pharma Data

AUGUST 24, 2020

They say genome sequencing shows the two strains of the virus are “clearly different”, making it the world’s first proven case of reinfection. Those infected develop an immune response as their bodies fight off the virus which helps to protect them against it returning. Getty Images.

Immune Response 52

Immune Response Genome Project Genome Genomics 52

Drug Discovery World

OCTOBER 16, 2023

Alchemab, on the other hand, has developed a highly differentiated platform which enables the identification of novel drug targets and therapeutics by analysis of patient antibody repertoires, drawing from the expertise in Cambridge to progress the company’s mission to build a broad pipeline of protective therapeutics for hard-to-treat diseases.

Drugs 75

Drugs Life Science Gene Therapy Genome 75

XTalks

FEBRUARY 11, 2021

The Human Genome Project recently marked 20 years since the publication of the first full sets of human genomic sequences, an endeavor that spanned well over a decade. Today, new next-generation sequencing technologies allow for the sequencing of complex genomes within just a day or two.

Genetics 119

Genetics DNA Genome Genomics 119

pharmaphorum

FEBRUARY 26, 2021

The field of medicine is riddled with challenges pertaining to diagnosis and finding treatment therapies for rare diseases. With only <10% of the affected people having treatment for their rare condition, the question remains – what impedes the process of developing a treatment for such diseases?

Drugs 58

Drugs Genome Project Genome Genomics 58

Drug Discovery World

JULY 19, 2023

Evan Floden , CEO of Seqera Labs examines how data sharing platforms are impacting cancer and genomics research. The tide has been turning in the worlds of diagnostics and drug development. A recent flurry of announcements indicates increasing interest and trust from major public health organisations in the power of genomics.

Genome 52

Genome Genomics Bioinformatics Genetics 52

Drug Discovery World

JULY 15, 2022

The first complete, gapless sequence of a human genome was published 1 April 2022 in a special issue of the journal Science 1. While The Human Genome Project mapped about 92% of the human genome two decades ago, sequencing the last 8% of the genome proved highly challenging.

Genome 52

Genome Genomics DNA Containment 52

Drug Discovery World

OCTOBER 6, 2022

Jarret Glasscock , PhD, CEO of Cofactor Genomics explains how diagnostics are emerging as the key to ensuring the right patients get matched to the right therapy, at the right time. . Precision medicine promises a paradigm shift to confidently match the right patients to the right treatment at the right time.

Medicine 52

Medicine Clinical Trials Clinical Trials Genome 52

Pharmaceutical Technology

AUGUST 26, 2008

As understanding of biological systems has forged ahead, pharmaceutical companies have made increasing use of biotechnology in discovering and manufacturing new medicines. The dynamic has now changed as many big companies have now acquired biotechnology companies or have developed ‘biotechnology divisions’ of their own.

Antibody 130

Antibody Licensing Licensing Production 130

Drug Discovery World

MARCH 6, 2024

The development of effective new disease-modifying treatments in neurodegenerative and neuropsychiatric disorders has been hindered by their inherent genetic complexity, environmental influences, and clinical variability.

Genome 64

Genome Genomics Clinical Trials Clinical Trials 64

The Pharma Data

APRIL 6, 2021

and European Union (EU) approvals, will also be presented, including long-term outcomes in patients with TRK fusion cancer receiving larotrectinib and data from the 100,000 Genomes Project analyzing the prognostic factor for survival for patients with tumors that harbor a neurotrophic receptor tyrosine kinase ( NTRK ) gene fusion.

Research 52

Research Genome Project Gene Genome 52