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Personalising whole genome sequencing doubles diagnosis of rare diseases 

Drug Discovery World

They subsequently applied additional bioinformatic approaches, using advanced computer technologies to identify genetic alterations in a patients’ DNA which may be causing disease but had been overlooked during routine testing. . It can also permit targeted screening of known disease complications and access to drug studies.

Genome 52
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International Women’s Day: Female life science leaders

Drug Discovery World

She founded Neuroute in 2019, with the aim of empowering patients from diverse backgrounds to participate in drug trials. Prior to Twist Bioscience, she worked at Agilent Technologies and at the University of Houston developing DNA and RNA parallel synthesis processes on solid support.

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Can liquid biopsies transform precision medicine?

Drug Discovery World

ctDNA is fragmented DNA released from dead or dying cancer cells, through the process of apoptosis or necrosis. ctDNA is fragmented DNA released from dead or dying cancer cells, through the process of apoptosis or necrosis. Use of clinical RNA-sequencing in the detection of actionable fusions compared to DNA-sequencing alone.

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Predictive diagnostics: closing the precision medicine gap

Drug Discovery World

Before drugs make it to market they have to pass through a gauntlet of stages involved in clinical trials. As such, patient selection for clinical trials has become an increasingly critical consideration for drug trial success.

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Recon: Sanofi, GKS report positive interim results for COVID shot; Regeneron resumes lymphoma trials

The Pharma Data

Regeneron resumes enrollment in lymphoma drug trials ( Reuters ). Incyte’s vitiligo treatment meets main goal in late-stage trial ( Reuters ). No To Five, Yes To Three: NICE Decides On Funding For Drugs In England ( Pink Sheet ). Trump tax law cut what US drugmakers owed.

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