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Patients of African heritage have fewer actionable mutations

Drug Discovery World

Genetic sequencing To assess these alterations in groups of different ancestries, Walch and colleagues analysed targeted DNA sequencing data from 4,441 patients treated for colorectal cancer at MSK between 2014 and 2022. Tumours were sequenced using MSK-IMPACT, a gene sequencing panel that looks for mutations in up to 505 genes.

Genome 52