DNA Packaging Protein RNA 
Scienmag
APRIL 14, 2021
In the cell nucleus histones play a crucial role packaging DNA into chromatin. Histones are however very sticky to both DNA and RNA, so to ensure they are transported to the cell nucleus after synthesis and bind to the right portion of DNA to organize the chromatin, they are guarded by complexes of histone chaperones. […].
The Pharma Data
MARCH 7, 2022
By combining CRISPR technology with a protein designed with artificial intelligence (AI), it is possible to awaken individual dormant genes by disabling the chemical “off switches” that silence them. Ruohola-Baker and Levy then fused this designed protein with a disabled version of a protein called Cas9. it can be reawakened.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Pfizer
AUGUST 15, 2022
Nirmatrelvir is designed to inhibit viral replication at a stage known as proteolysis, which occurs before viral RNA replication. In preclinical studies, nirmatrelvir did not demonstrate evidence of mutagenic DNA interactions. Microsomal triglyceride transfer protein inhibitor: lomitapide. Immunosuppressants: voclosporin.
Drug Discovery World
MAY 2, 2023
Steve Wowk , VP, Business Unit and General Management of Integrated DNA Technologies, shared with DDW the value of CRISPR-Cas9 in drug discovery. In an effort to defend themselves against viral infection, bacterial cells capture and copy DNA fragments of bacteriophages into their genome. CRISPR libraries: Why do we need them?
Drug Discovery World
JULY 18, 2023
Rolf Turk , Senior Manager, Genomics Medicine at Integrated DNA Technologies, examines how CRISPR is being used to enhance cancer therapies. CRISPR diagnostics have successfully detected various pathogens, including RNA viruses (eg. parvovirus B19, Flaviviridae, Ebola, and Coronaviridae), DNA viruses (e.g.,
XTalks
FEBRUARY 11, 2021
The drugmaker is targeting various steps in the manufacturing process, beginning right at the DNA stage, which is required as the template from which the mRNA for the SARS-CoV-2 spike protein in the vaccine is made. This involves testing and quality assurance of the DNA to make sure its integrity meets the strict vaccine requirements.
The Pharma Data
SEPTEMBER 1, 2020
About antigen testing An antigen test detects proteins which are structural or functional components of a pathogen and are thus very specific to that pathogen. SARS-CoV-2 Rapid Antigen Test package insert [2] European Centre for Disease Prevention and Control. Results are ready in only 15 minutes. References [1] Roche Diagnostics Ltd.
Expert insights. Personalized for you.
40 
Let's personalize your content