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Enabling the next wave of innovative drug therapies with speciality enzymes

Pharmaceutical Technology

The next wave of medicine is well on course to be cell and gene-based. Continuing advancements within this field deliver new hope to doctors and patients, transforming disease outcomes for previously incurable indications. And it’s within the family – Novozymes!”. This venture is a perfect match; we complement each other.

Drugs 295
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Advancements in upstream CLD for enhanced biotherapeutics production

Drug Discovery World

Upstream cell line development has seen notable progress with recent advances in cell line engineering, particularly in enhancing gene of interest integration specificity, clone selection, and production efficiency. Next-generation engineering tools, such as gene editing have enabled knock-out cell lines with enhanced characteristics.

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Rheumatoid arthritis treated with implanted cells that release drug

The Pharma Data

Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation. The engineered cells reduced inflammation and prevented a type of damage to bone, known as bone erosion, in a mouse model of rheumatoid arthritis. million adults in the United States.

Drugs 52
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A history of blood cancer treatment

pharmaphorum

Thanks to the dedicated efforts of doctors, patients, carers, and healthcare professionals, people diagnosed with blood cancer are now living longer, with a steady stream of more effective treatments entering the market each year. However, myelodysplastic syndromes and myeloproliferative neoplasms are also prominent types of blood cancer.

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The evolution of assays for immuno-oncology research

Drug Discovery World

Genetically engineered mouse models (GEMM) recapitulate the stromal biology of different human cancers including the tumour microenvironment that regulates the disease process. Genetically engineered mouse models in oncology research and cancer medicine. Multiple methods exist for generating 3D culture models.

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What to expect from PEGS Europe 2023: Day 2

Drug Discovery World

Alessa Schaffrath, Doctoral Student, UKE Hamburg, on: ‘Transgenic llama mice – a fast and flexible single domain discovery tool’. Marine Houdou, Genetic Engineering Specialist, Polyplus, on: ‘From modular DNA assembly to recombinant protein production at Polyplus’.