AuroBlog - Aurous Healthcare Clinical Trials blog

NOVEMBER 1, 2023

The Drug Controller General of India (DCGI) has added in-vitro diagnostic (IVD) medical devices including those for diagnosis of Covid-19, ribonucleic acid (RNA) and deoxyribonucleic acid (DNA) extraction kits, among others into the Class C risk category under the Medical Devices Rules (MDR), 2017.

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Pharma Mirror

MARCH 8, 2021

The post The drug Fenbendazole can make tumors sensitive to radiotherapy just like agents of chemotherapy appeared first on Pharma Mirror Magazine. 2] Presumably, fenbendazole multitherapy along with this little. 2] Presumably, fenbendazole multitherapy along with this little.

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Drug Discovery World

AUGUST 9, 2023

Join DDW for this exclusive free event, Are in vitro metabolism and drug-drug interaction studies critical for an investigational new drug application? Participants will gain insight into the specific needs and utility for in vitro ADME and DDI investigations in the drug development process.

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BioTech 365

JANUARY 28, 2021

Charles River Announces Strategic Partnership with Cypre, Expanding 3D In Vitro Services for Cancer Immunotherapy and Targeted Therapy Drug Screening Charles River Announces Strategic Partnership with Cypre, Expanding 3D In Vitro Services for Cancer Immunotherapy and Targeted Therapy Drug Screening … Continue reading →

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BioSpace

JULY 19, 2021

Preclinical data for its drug candidate, LP-184, reportedly showed over 90 percent efficacy in shrinking pancreatic cancer tumors in mouse models in vitro, in-vivo, and ex-vivo.

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Drug Discovery World

AUGUST 23, 2023

Join DDW for this exclusive free event, Are in vitro metabolism and drug-drug interaction studies critical for an investigational new drug application? Participants will gain insight into the specific needs and utility for in vitro ADME and DDI investigations in the drug development process.

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Drug Discovery World

AUGUST 16, 2023

Join DDW for this exclusive free event, Are in vitro metabolism and drug-drug interaction studies critical for an investigational new drug application? Participants will gain insight into the specific needs and utility for in vitro ADME and DDI investigations in the drug development process.

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Pharmaceutical Technology

APRIL 7, 2023

Enanta Pharmaceuticals has secured the US Food and Drug Administration’s (FDA) fast track designation for EDP-323 to treat respiratory syncytial virus (RSV). In vitro data of EDP-323 showed a significant reduction in RSV replication with picomolar potency in primary human bronchial epithelial cells against RSV A and B.

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Pharmaceutical Technology

FEBRUARY 23, 2023

In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Artificial Intelligence in Pharmaceuticals: In-silico drug discovery. However, not all innovations are equal nor do they follow a constant upward trend.

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Drug Discovery World

OCTOBER 4, 2023

Embark on an in-depth journey through the pivotal Make-Test-Decide Workflow, where collaboration and data-driven decisions play a paramount role in the intricate landscape of drug discovery. This on-demand webinar shows how cloud implementation fosters accessibility and collaboration, revolutionising research across locations and companies.

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FDA Law Blog

MARCH 19, 2024

(HP&M), the largest dedicated food and drug law firm in the U.S., Mullen’s extensive experience and contributions to the field of in vitro diagnostic (IVD) regulation. AMDM facilitates educational resources within the in vitro diagnostic industry. This prestigious appointment recognizes Ms.

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Drug Discovery World

NOVEMBER 15, 2022

Many of the most promising areas of drug development in this field target neuroinflammation and remyelination. Discover how in vitro assays can be used to model in vivo neurodegeneration. Learn how to select the most appropriate assay for your drug target of interest.

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Drug Discovery World

SEPTEMBER 1, 2022

These sequence-defined, recombinant antibodies are suitable for developing highly selective and sensitive pharmacokinetic (PK) and anti-drug antibody (ADA) assays for evolocumab and its biosimilars. The post New anti-evolocumab antibodies could aid drug development appeared first on Drug Discovery World (DDW).

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Drug Discovery World

NOVEMBER 15, 2022

Many of the most promising areas of drug development in this field target neuroinflammation and remyelination. Discover how in vitro assays can be used to model in vivo neurodegeneration. Discover how in vitro assays can be used to model in vivo neurodegeneration. Watch the webinar now.

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In-Vitro Drugs In-Vivo Life Science 52

Drug Discovery World

OCTOBER 4, 2023

Watch this new webinar to embark on an in-depth journey through the pivotal Make-Test-Decide Workflow, where collaboration and data-driven decisions play a paramount role in the intricate landscape of drug discovery.

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In-Vivo In-Vitro Drugs Research 52

Medical Xpress

JANUARY 26, 2023

Bioengineered artificial skin has become an increasingly important and reliable platform for researchers to test the safety and efficacy of drugs and cosmetics. The most promising technologies for production of in vitro models include 3D bioprinting. It can be produced on a large scale and is a good substitute for animal testing.

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Drug Discovery World

AUGUST 30, 2023

Join DDW for this exclusive free event, Are in vitro metabolism and drug-drug interaction studies critical for an investigational new drug application? Participants will gain insight into the specific needs and utility for in vitro ADME and DDI investigations in the drug development process.

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Drug Discovery World

FEBRUARY 13, 2024

AM1476, a first-in-class, peripheral-acting serotonin receptor antagonist, has been granted US and EU Orphan Drug Designation as an anti-fibrotic treatment for systemic sclerosis. It has demonstrated efficacy in in vitro and in vivo models of fibrosis, as well as favourable safety and pharmacokinetic profiles in Phase I clinical studies.

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Pharmaceutical Technology

MAY 4, 2023

Vertex Pharmaceuticals has received approval from the US Food and Drug Administration (FDA) for KALYDECO (ivacaftor) to treat children with cystic fibrosis (CF) aged between one and four months. This cohort showed a safety profile identical to that found in older children and adults.

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The Pharma Data

OCTOBER 16, 2020

This week’s round up features a digital solution for adapting clinical trials to ease the burden on the clinical research industry and an in vitro model that mimics the human airway epithelium using a newly developed technology platform. In vitro antiviral technology proves effective against SARS-CoV-2 in human airway infection model.

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Scienmag

NOVEMBER 18, 2020

(November 18, 2020)–Researchers at the University of Tennessee Health Science Center working with colleagues at the University of New Mexico have identified three drugs, already approved for other uses in humans, as possible therapeutics for COVID-19, the illness caused by the SARS-CoV-2 virus.

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Drug Discovery World

JUNE 30, 2023

Research tools, safety testing and regenerative medicines – these endless stem cell applications are powering precision, speed, and new modalities in drug development. Stem cells for use in drug discovery Stem cells are fast becoming an invaluable tool in the drug discovery process.

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Drug Discovery World

APRIL 21, 2023

New study results have demonstrated the potential of a new drug to reprogramme the immune profile in the tumour microenvironment (TME) and convert resistant tumours to responders to Immune Checkpoint Blockage (ICB) therapies. The post New drug could help overcome tumour resistance to treatment appeared first on Drug Discovery World (DDW).

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Drug Discovery World

APRIL 25, 2023

Download our mitochondrial toxicity infographic and discover the benefits of novel in vitro strategies for consumer safety. Drug-induced mitochondrial dysfunction has been linked to compound attrition, organ toxicity, black-box warnings, and market withdrawals. Understand the importance of testing in early-phase drug discovery.

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Drug Discovery World

APRIL 25, 2023

Download this new mitochondrial toxicity infographic by Agilent and discover the benefits of novel in vitro strategies for consumer safety. Drug-induced mitochondrial dysfunction has been linked to compound attrition, organ toxicity, black-box warnings, and market withdrawals. Download now.

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Drug Discovery World

OCTOBER 18, 2023

The platform aims to overcome the limitations associated with adherent cell culture and assaying workflows by enabling small colonies of cells to be moved and frozen in their adherent state, increasing the volume of data collected per experiment and reducing the resource demands of in vitro drug discovery.

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Drug Discovery World

JUNE 8, 2023

Grown in vitro, these cells can provide patient specific human brain models from a large cohort of AD patients – to create a ‘clinical trial in a dish’. The recent US Federal Food and Drug Administration Agency (FDA) Modernization Act 2.0

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Pharmaceutical Technology

MAY 31, 2023

According to GlobalData, Phase I drugs for Solid Tumor have a 54% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how ZNA-1041’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

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Drug Discovery World

MARCH 24, 2023

A new study has found that highly purified gelatin biomaterials could enhance the reliability and reproducibility of 3AD in vitro models, creating new possibilities for replacing preclinical animal trials. This can improve the validity of 3D in vitro models and help to reduce animal testing.”

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Drug Discovery World

JANUARY 18, 2023

The US Food and Drug Administration (FDA) and CN Bio have expanded their collaboration for the second time, with new research aiming to evaluate multi-organ microphysiological systems (MPS) using the PhysioMimix Multi-organ System. . Bioavailability is defined as the fraction of drug reaching the bloodstream.

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XTalks

JUNE 26, 2023

Medical device and in vitro diagnostics technologies provider SurModic Inc. has announced that its new drug-coated balloon (DCB) SurVeil has been granted approval by the US Food and Drug Administration (FDA). SurVeil has an edge over IN.PACT as it is coated with a lower dose of the drug.

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pharmaphorum

FEBRUARY 13, 2022

German drugmaker Merck KGaA has reached an agreement to pilot an artificial intelligence platform developed by Quris that aims to identify potential safety problems with new therapeutic candidates as early as possible in the drug discovery process.

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Drug Discovery World

JANUARY 3, 2023

Mersana Therapeutics and a subsidiary of Merck have entered a research collaboration to discover novel Immunosynthen antibody-drug conjugates (ADCs) directed against up to two targets. . The post Research partners hope to develop novel antibody-drug conjugates appeared first on Drug Discovery World (DDW).

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Drug Discovery World

APRIL 5, 2023

Italian research institute and contract research organisation IRBM has become the only company from outside the United States to join cancer drug discovery network the Chemical Biology Consortium (CBC). The post Only non-US company joins cancer drug discovery consortium appeared first on Drug Discovery World (DDW).

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Drug Discovery World

JUNE 6, 2023

(retinoic acid receptor alpha beta) biased agonist and will now enter investigational new drug (IND)-enabling studies. ” The post BenevolentAI progresses drug for the potential treatment of ALS appeared first on Drug Discovery World (DDW).

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XTalks

APRIL 14, 2022

Conventional in vitro and in vivo studies are used in the drug development pipeline. This involves the use of an individualized computer simulation for medical device or drug development. Therefore, companies can evaluate their drug candidates or medical device products in “virtual patients” before assessing them in humans.

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Pharmaceutical Technology

NOVEMBER 4, 2022

The staff in the US from the acquired business will be retained by Reaction to set up its presence in Hershey, which comprises in vitro and in vivo expertise. The staff in the US from the acquired business will be retained by Reaction to set up its presence in Hershey, which comprises in vitro and in vivo expertise. at closing.

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