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In-Vivo Gene Editing RNA Packaging DNA Genomics Genome Gene Therapy Bacteria Genetics More Related Topics >
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CRISPR breakthroughs: New solutions for common diseases

Drug Discovery World

JULY 18, 2023

Current research is focused on designing CRISPR-enhanced CAR T cells that are resistant to immunosuppressive cytokines such as transforming growth factor-β (TGF-β) 2 , programmed cell death protein (PD-1) 3 , or other negative T cell regulators 4 (CTLA-4, LAG-3, and TIM-3), thus improving anti-tumour functions.

DNA 98
DNA Genome Genomics RNA 98
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Delivering on the promise of gene editing

Drug Discovery World

DECEMBER 15, 2022

Potential solutions: For CRISPR systems, the likelihood of off-target editing has been shown to be influenced by a variety of factors, ranging from the design of the gRNA 1 and Cas9 protein 2 , to the targeted cell type 3 , to name a few examples.

Gene Editing 52
Gene Editing Gene In-Vivo Genome 52
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