Genetics, Radiology, Research and Trials - Clinical Research Informer

World Cancer Day 2024: Trends in Oncology Research and More

XTalks

JANUARY 26, 2024

Technological advancements are revolutionizing cancer research and therapies. By editing these genes, researchers can effectively neutralize their cancer-promoting effects. By tailoring treatments based on an individual’s genetic makeup, it may allow for more effective and targeted therapies.

Research

Research Gene Editing Gene Genetics

AZD1222 US Phase III trial met primary efficacy endpoint in preventing COVID-19 at interim analysis

The Pharma Data

MARCH 22, 2021

The AstraZeneca US Phase III trial of AZD1222 demonstrated statistically significant vaccine efficacy of 79% at preventing symptomatic COVID-19 and 100% efficacy at preventing severe disease and hospitalisation. The trial had a 2:1 randomisation of vaccine to placebo. The specific search for CVST found no events in this trial.

Trials

Trials Vaccination Vaccine Radiology

The Utility of Liquid Biopsy in Oncology Clinical Trials

XTalks

NOVEMBER 7, 2022

“Liquid biopsies have demonstrated promising activity in multiple clinical settings, but the great enthusiasm and expectations around them can be harmful if not adequately managed,” said Dr. El Mustapha Bahassi, PhD, Director, Clinical Laboratory Sciences, at the global clinical research organization (CRO) Medpace. cfDNA Isolation Techniques.

Clinical Trials

Clinical Trials Clinical Trials Trials FDA Approval

A USD 4.2 Billion Myovant/ Pfizer Deal; Audentes Therapeutics’ ASPIRO Trial Free to Proceed; First Generic of Drug for Severe Hypoglycemia Gets Approval; Teleflex Acquires Z-Medica

Delveinsight

DECEMBER 29, 2020

Audentes Therapeutics’ ASPIRO Trial Free to Proceed. The Food and Drug Administration (FDA) decided to lift the clinical ban from Audentes Therapeutics’ ASPIRO trial, which was aimed at investigating its AT132 for the treatment of X-linked myotubular myopathy (XLMTM), a rare neuromuscular disease. . The post A USD 4.2

Trials

Trials Drugs Hormones Radiology

What will the 2023 drug discovery landscape look like?

Drug Discovery World

JANUARY 24, 2023

Virtual clinical trials ‘Virtual’ and ‘technology’ are concepts which are readily exchanged in this industry, but these are more than just buzzwords. The overall virtual clinical trials market is currently valued at $7.8 In early November 2022, two Alzheimer’s drugs were tested head-to-head in a first-ever virtual clinical trial 3.

Clinical Trials

Clinical Trials Clinical Trials Drugs Trials

Who are the AACR Scientific Achievement Award winners?

Drug Discovery World

APRIL 14, 2023

The American Association for Cancer Research (AACR) will honour the following cancer researchers, physician-scientists, advocates, and journalists during its annual meeting to be held April 14-19 at the Orange County Convention Center in Orlando, Florida. June’s award lecture will be held on Sunday April 16 at 4:30pm ET.

Genetics

Genetics Research Medicine Clinical Research

AZD1222 US Phase III primary analysis confirms safety and efficacy

The Pharma Data

MARCH 24, 2021

Positive high-level results from the primary analysis of the Phase III trial of AZD1222 in the US have confirmed vaccine efficacy consistent with the pre-specified interim analysis announced on Monday 22 March 2021. The NIAID-supported COVID-19 Prevention Network (CoVPN) participated in the trial. D8110C00001 1.

Radiology

Radiology Vaccination Vaccine Trials

Scrutinizing the West Syndrome Market Space from Growth Perspectives

Delveinsight

SEPTEMBER 27, 2021

It can be due to the previous existence of brain damage signs (psychomotor retardation, neurologic signs, radiologic signs, or other types of seizures) or on the basis of etiology that is characterized by a lack of previous signs of brain damage. There are many different causes of epileptic spasms. before the onset of the spasm.

Marketing

Marketing Hormones Radiology Pharma Companies

Considerations for Neuroscience Trials with Intrathecal Delivery and Other Methods of Direct CNS Administration

XTalks

AUGUST 30, 2022

Clinical research experts from the CRO Medpace shared insights about the operational and regulatory considerations for neuroscience trials with direct CNS administration. In a recent webinar, Dr. Vornov described the history and current progress in targeted CNS therapeutic delivery. Why is it Difficult to Develop CNS Therapeutics?

Trials

Trials Drug Delivery Drugs Gene

FDA Approves First Rapid COVID Test for Home Use

The Pharma Data

NOVEMBER 18, 2020

The California company said that clinical trials showed 100% of patients were able to perform the Lucira test in about two minutes. Lab tests that look for the coronavirus’s genetic material using a technique called polymerase chain reaction (PCR) are still considered the gold standard for detecting the virus. percent effective.

FDA Approval

FDA Approval Vaccination Vaccine Genetics

Hypoxia-Inducible Factor-2 Alpha (HIF-2?) Inhibitor WELIREG™ (belzutifan) for the Treatment of Patients With Certain Types of Von Hippel-Lindau (VHL) Disease-Associated Tumors

The Pharma Data

AUGUST 15, 2021

The approval is based on results from the open-label Study 004 trial (N=61), where the major efficacy endpoint was overall response rate (ORR) in patients with VHL-associated RCC. The major efficacy endpoint for the treatment of VHL-associated RCC was ORR measured by radiology assessment using RECIST v1.1 WELIREG is the first HIF-2?

Hormones

Hormones Clinical Trials Clinical Trials Trials

Sunday 16 April at AACR Annual Meeting 2023

Drug Discovery World

APRIL 16, 2023

DDW’s Megan Thomas rounds up highlights from Sunday 16 April at AACR 2023, from promising trial results for a personalised mRNA-based cancer vaccine to winners of lifetime achievement awards.

Clinical Trials

Clinical Trials Clinical Trials Research Vaccination

AstraZeneca’s COVID-19 vaccine; Type 1 diabetes research updates; FDA nod to Zebra’s X-ray modelling AI; UniQure/CSL haemophilia B gene therapy curbs bleeding in phase 3

Delveinsight

DECEMBER 10, 2020

The full data from late-phase trials of AstraZeneca’s COVID-19 vaccine have pointed to the potential for AZD1222 to work after a single dose and limit asymptomatic cases; however, missed main questions regarding the efficacy of the candidate. In a pooled analysis of 11,636 participants enrolled in two separate clinical trials in the U.K.

Gene Therapy

Gene Therapy Gene Vaccination Vaccine

AZD7442 PROVENT Phase III prophylaxis trial met primary endpoint in.

The Pharma Data

AUGUST 22, 2021

The trial accrued 25 cases of symptomatic COVID-19 at the primary analysis.There were no cases of severe COVID-19 or COVID-19-related deaths in those treated with AZD7442. The trial included 5,197 participants in a 2:1 randomisation AZD7442 to placebo. The trial was conducted in 87 sites in the US, UK, Spain, France and Belgium.

Trials

Trials Antibody Vaccination Vaccine

FDA accepts Pfizer’s Supplemental New Drug Applications for BRAFTOVI + MEKTOVI

The Pharma Data

APRIL 7, 2023

” These sNDAs are supported by results from the PHAROS trial (NCT03915951), an open-label, multicenter, non-randomized, Phase 2 study (n=98) to determine the safety, tolerability, and efficacy of BRAFTOVI given in combination with MEKTOVI in patients with BRAF V600E-mutant metastatic NSCLC. International Agency for Research on Cancer.

FDA Approval

FDA Approval Drugs Medicine Genetics

Birx Says U.S. COVID Cases Are Skyrocketing as Holidays Approach

The Pharma Data

NOVEMBER 20, 2020

The California company said that clinical trials showed 100% of patients were able to perform the Lucira test in about two minutes. Lab tests that look for the coronavirus’s genetic material using a technique called polymerase chain reaction (PCR) are still considered the gold standard for detecting the virus. percent effective.

Vaccination

Vaccination Vaccine Genetics Radiology

COVID-19 Pandemic Coverage

XTalks

SEPTEMBER 14, 2020

By the end of August, the World Health Organization (WHO) counted 33 vaccine candidates in some stage of clinical trial evaluation. As of July, the company and its federal partner stated that it is on track to supply between 500 million to 1 billion doses a year at a dose of 100 µg now selected for their Phase III trial.

Vaccination

Vaccination Vaccine Antibody Life Science

Clinical Research Informer

World Cancer Day 2024: Trends in Oncology Research and More

AZD1222 US Phase III trial met primary efficacy endpoint in preventing COVID-19 at interim analysis

Trending Sources

The Utility of Liquid Biopsy in Oncology Clinical Trials

A USD 4.2 Billion Myovant/ Pfizer Deal; Audentes Therapeutics’ ASPIRO Trial Free to Proceed; First Generic of Drug for Severe Hypoglycemia Gets Approval; Teleflex Acquires Z-Medica

What will the 2023 drug discovery landscape look like?

Who are the AACR Scientific Achievement Award winners?

AZD1222 US Phase III primary analysis confirms safety and efficacy

Scrutinizing the West Syndrome Market Space from Growth Perspectives

Considerations for Neuroscience Trials with Intrathecal Delivery and Other Methods of Direct CNS Administration

FDA Approves First Rapid COVID Test for Home Use

Hypoxia-Inducible Factor-2 Alpha (HIF-2?) Inhibitor WELIREG™ (belzutifan) for the Treatment of Patients With Certain Types of Von Hippel-Lindau (VHL) Disease-Associated Tumors

Sunday 16 April at AACR Annual Meeting 2023

AstraZeneca’s COVID-19 vaccine; Type 1 diabetes research updates; FDA nod to Zebra’s X-ray modelling AI; UniQure/CSL haemophilia B gene therapy curbs bleeding in phase 3

AZD7442 PROVENT Phase III prophylaxis trial met primary endpoint in.

FDA accepts Pfizer’s Supplemental New Drug Applications for BRAFTOVI + MEKTOVI

Birx Says U.S. COVID Cases Are Skyrocketing as Holidays Approach

COVID-19 Pandemic Coverage

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