The Pharma Data

MARCH 22, 2021

The AstraZeneca US Phase III trial of AZD1222 demonstrated statistically significant vaccine efficacy of 79% at preventing symptomatic COVID-19 and 100% efficacy at preventing severe disease and hospitalisation. The trial had a 2:1 randomisation of vaccine to placebo. The specific search for CVST found no events in this trial.

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Pharmaceutical Technology

NOVEMBER 30, 2022

Development of vaccines to Phase I trials under the five-year $59m prototype project comprises additional $28.4m Additionally, the funds are intended to advance the vaccines to successful conclusion of Phase I clinical trials. in milestone payments.

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Drug Discovery World

NOVEMBER 29, 2023

Researchers have created a mathematical model that can accurately depict Alzheimer’s disease progression in individual patients, paving the way for personalised treatment and faster development of therapies. These findings closely matched the results of the corresponding real-life clinical trials.

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The Pharma Data

FEBRUARY 21, 2022

Bayer’s research and development pipeline continues to grow as the company is building on its existing competencies, such as the expertise around small molecules, while expanding into new modalities, including cell and gene therapies. Re-imagining Radiology. In particular, AI bears vast potential for advancing radiology.

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The Pharma Data

DECEMBER 14, 2020

Phase II Small Business Innovation Research (SBIR) grant from the National Institute of Neurological Disorders and Stroke (NINDS) of the National Institutes of Health (NIH). LA JOLLA, Calif. , 15, 2020 /PRNewswire/ — Alume Biosciences, Inc. Alume) announced today that it has been awarded a $2.5M About Alume Biosciences, Inc.

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Clinical Trials Clinical Trials Trials Radiology 52

Advarra

APRIL 30, 2024

Maintaining complete and compliant documentation while managing the complex processes and interactions of clinical trial conduct is complicated. Investigator Site Files The ISF contains essential documents permitting evaluation of a clinical trial’s conduct. associates, residents, research fellows). based sites.

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Delveinsight

DECEMBER 29, 2020

Audentes Therapeutics’ ASPIRO Trial Free to Proceed. The Food and Drug Administration (FDA) decided to lift the clinical ban from Audentes Therapeutics’ ASPIRO trial, which was aimed at investigating its AT132 for the treatment of X-linked myotubular myopathy (XLMTM), a rare neuromuscular disease. . The post A USD 4.2

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XTalks

NOVEMBER 29, 2022

Last week , researchers at the Yale School of Medicine reported that they have identified brain biomarkers of attention-deficit/hyperactivity disorder (ADHD) in children. The study results will be presented at the Radiological Society of North America annual meeting , which is currently being held in Chicago, IL until December 1, 2022.

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Drug Discovery World

JANUARY 24, 2023

Virtual clinical trials ‘Virtual’ and ‘technology’ are concepts which are readily exchanged in this industry, but these are more than just buzzwords. The overall virtual clinical trials market is currently valued at $7.8 In early November 2022, two Alzheimer’s drugs were tested head-to-head in a first-ever virtual clinical trial 3.

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Clinical Trials Clinical Trials Drugs Trials 97

XTalks

JUNE 30, 2023

“The approval of Ultravist-300 and -370 in contrast-enhanced mammography gives physicians a new imaging option where conventional mammography might not be enough,” said Dr. Konstanze Diefenbach, head of Radiology Research and Development at Bayer, in the company’s news release. “We What is Contrast-Enhanced Mammography (CEM)?

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Drug Discovery World

APRIL 8, 2024

The American Association of Cancer Research (AACR) Annual Meeting launched on Sunday 7 April in San Diego with an Opening Plenary Session showcasing cutting-edge technological advances opening new frontiers in cancer science.

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The Pharma Data

MARCH 24, 2021

Positive high-level results from the primary analysis of the Phase III trial of AZD1222 in the US have confirmed vaccine efficacy consistent with the pre-specified interim analysis announced on Monday 22 March 2021. The NIAID-supported COVID-19 Prevention Network (CoVPN) participated in the trial. D8110C00001 1.

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WCG Clinical

MARCH 17, 2023

With many clinical research sites facing study start-up delays and backlogs, performing a coverage analysis efficiently and thoroughly is critical to the study start-up process. But why is the coverage analysis process so vital for clinical trials and how can research sites do it more effectively?

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Compliance Clinical Trials Clinical Trials Trials 52

Cloudbyz

APRIL 4, 2023

Source documents and case report forms (CRFs) are two types of documents that are commonly used in clinical trials to collect clinical data. On the other hand, CRFs are electronic forms used to collect and manage clinical data in clinical trials. This can impact the accuracy and reliability of the data extracted.

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Clinical Trials Clinical Trials Containment Radiology 52

Drug Discovery World

OCTOBER 24, 2022

“We did a deep dive through over 1100 treatments across preclinical models and never found results where the tumours shrank away and disappeared like ours did,” said Jeff Schaal, who conducted the research during his PhD in the laboratory of Ashutosh Chilkoti , the Alan L Kaganov Distinguished Professor of Biomedical Engineering at Duke. .

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pharmaphorum

SEPTEMBER 8, 2022

As Kerry Capozza, Founder and Executive Director of Global Parents for Eczema Research explains, “There’s no easy solution, unless the eczema can be treated and brought under control”. As yet, no new medical product has been approved on the basis of a digital endpoint.

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The Pharma Data

OCTOBER 1, 2021

The phase IV clinical trials , multicenter, controlled, cross-over study with corresponding blinded image evaluations met its primary endpoint, showing that a 75 percent dose of gadobutrol (0.075 mmol/kg) is non-inferior to a one hundred pc dose of gadoterate (0.1 Dr. Olaf Weber, Head of Radiology Research and Development at Bayer.

Radiology 52

Radiology Life Science Development Production 52

Drug Discovery World

APRIL 14, 2023

The American Association for Cancer Research (AACR) will honour the following cancer researchers, physician-scientists, advocates, and journalists during its annual meeting to be held April 14-19 at the Orange County Convention Center in Orlando, Florida. June’s award lecture will be held on Sunday April 16 at 4:30pm ET.

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The Pharma Data

MARCH 29, 2022

Evusheld significantly reduced the risk of developing symptomatic COVID-19 in PROVENT Phase III trial, with protection lasting at least six months Evusheld retains neutralising activity against the Omicron BA.2 1-3 Evusheld was generally well-tolerated in the trial. Evusheld was generally well-tolerated in the trials.

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XTalks

AUGUST 30, 2022

Clinical research experts from the CRO Medpace shared insights about the operational and regulatory considerations for neuroscience trials with direct CNS administration. In a recent webinar, Dr. Vornov described the history and current progress in targeted CNS therapeutic delivery. Why is it Difficult to Develop CNS Therapeutics?

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FDA Law Blog

FEBRUARY 28, 2022

The Agency envisions a range of activities that may enhance the design and conduct of clinical studies through engagement with “patient advisors” – individuals who have experience living with a disease or condition, but who are not study/research participants themselves or caregivers of study/research participants.

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The Pharma Data

OCTOBER 22, 2020

reflect the shared commitment of Gilead, government agencies and clinical trial investigators to advance well-tolerated, effective treatment options for the fight against COVID-19. The ACTT-1 trial results are complemented by results of two Phase 3 open-label trials of Veklury conducted in adult patients with severe and moderate COVID-19.

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Bioengineer

JULY 15, 2021

“In clinical trials, we tend to go with the maximum tolerable dose, the idea being that radiation kills the cancer and the more we give, the better. In both animal studies, the researchers used a novel agent that can target nearly any type of cancer, including tumors at any location within the body. ” ###. Jonathan W.

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Delveinsight

SEPTEMBER 27, 2021

It can be due to the previous existence of brain damage signs (psychomotor retardation, neurologic signs, radiologic signs, or other types of seizures) or on the basis of etiology that is characterized by a lack of previous signs of brain damage. There are many different causes of epileptic spasms.

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The Pharma Data

MARCH 25, 2022

2-4 Evusheld was generally well-tolerated in the trial.(2-4). The half-life extension more than triples the durability of its action compared to conventional antibodies;(11-13) data from the PROVENT Phase III trial show protection lasting at least six months.(14) Evusheld was well-tolerated in the trials. W911QY-21-9-0001.

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Antibody In-Vivo Medicine Vaccination 52

The Pharma Data

DECEMBER 23, 2020

Joseph Kim , President and CEO of INOVIO, said, “We are very pleased to share peer-reviewed Phase 1 clinical data for INO-4800 published in The Lancet’s EClinicalMedicine , and are grateful for the support of all participants and investigator staff involved in the clinical trial.” . PLYMOUTH MEETING, Pa. ,

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The Pharma Data

APRIL 17, 2021

Biogen advances leading research to help inform future patient management including new information on the clinical profile of extended interval dosing with natalizumab. The research adds to the vast clinical knowledge Biogen continues to advance as part of its commitment to the care of people living with MS. CAMBRIDGE, Mass.,

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Clinical Trials Clinical Trials Trials Radiology 52

Triage Cancer

OCTOBER 15, 2020

In some cases, participating in a clinical trial may or may not be covered by a pharmaceutical company. Be diligent and do your own research before signing a consent form for a specific treatment. Having this information will be helpful when researching the treatment on your own later. Clinical Trial Participation.

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Clinical Trials Clinical Trials Trials Doctors 52

The Pharma Data

NOVEMBER 9, 2021

Still, the recommended cure for molnupiravir grounded on the Phase 3 MOVe- OUT clinical trial would be 800 mg doubly daily for five days, If authorized or approved.

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Medicine Radiology Development Drugs 52

The Pharma Data

NOVEMBER 18, 2020

The California company said that clinical trials showed 100% of patients were able to perform the Lucira test in about two minutes. The trial results — delivered less than a year after researchers began working on the vaccine — shattered all speed records for vaccine development, the Times reported. .”

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pharmaphorum

APRIL 7, 2021

It’s also providing research funding. Meanwhile, it also has a candidate in late-stage testing, called Lu-PSMA-617, which improved survival in PSMA-positive castration-resistant prostate cancer (CRPC) in a phase 3 trial last month and has been billed as a future blockbuster. That was acquired from Endocyte in 2018 in a $2.1

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DNA Licensing Licensing Gene Therapy 52

The Pharma Data

AUGUST 15, 2021

The approval is based on results from the open-label Study 004 trial (N=61), where the major efficacy endpoint was overall response rate (ORR) in patients with VHL-associated RCC. The major efficacy endpoint for the treatment of VHL-associated RCC was ORR measured by radiology assessment using RECIST v1.1 WELIREG is the first HIF-2?

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Hormones Clinical Trials Clinical Trials Trials 52

The Pharma Data

NOVEMBER 18, 2021

Six-months follow-up of prevention trial showed 83% reduced risk of symptomatic COVID-19, with no severe disease or deaths with AZD7442. Separate treatment trial showed 88% reduced risk of severe COVID-19 or death when treated within three days of symptom onset.

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Trials Antibody In-Vitro Vaccination 52

Drug Discovery World

APRIL 16, 2023

DDW’s Megan Thomas rounds up highlights from Sunday 16 April at AACR 2023, from promising trial results for a personalised mRNA-based cancer vaccine to winners of lifetime achievement awards.

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Clinical Trials Clinical Trials Research Vaccination 52

Delveinsight

SEPTEMBER 2, 2021

XACT Robotics declares completion of enrollment in a pilot trial evaluating the use of its Robotic System to perform CT-Guided percutaneous procedures in the Lung.

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The Pharma Data

OCTOBER 12, 2021

Trial met primary endpoint. The trial met the primary endpoint, with a cure of 600 mg of AZD7442 given by intramuscular (IM) injection reducing the threat of developing severe COVID-19 or death (from any cause) by 50 compared to placebo in rehabilitants who had been characteristic for seven days or lower.

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Trials Development Antibody Radiology 52

Delveinsight

DECEMBER 10, 2020

The full data from late-phase trials of AstraZeneca’s COVID-19 vaccine have pointed to the potential for AZD1222 to work after a single dose and limit asymptomatic cases; however, missed main questions regarding the efficacy of the candidate. In a pooled analysis of 11,636 participants enrolled in two separate clinical trials in the U.K.

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